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ALS (Amyotrophic Lateral Sclerosis) — Deal Benchmarks & Valuation

Median Upfront
$433M
Range: $214M - $659M
Total Deal Value
$3.9B
Range: $2.3B - $5.5B
Royalty Rate
13.3% - 21.3%
Tiered up to 25.3%
Dev Milestones
$1.1B
Range: $701M - $1.6B

Market Analysis

ALS (Amyotrophic Lateral Sclerosis) is one of the most actively transacted indications in neurology licensing. Phase 2 deals for als (amyotrophic lateral sclerosis) carry a median total deal value of $3.9B, with upfront payments ranging from $214M to $659M. The recommended deal structure allocates approximately 11% to upfront payments and 89% to milestones.

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Frequently Asked Questions

What are typical deal terms for als (amyotrophic lateral sclerosis) licensing?
Phase 2 als (amyotrophic lateral sclerosis) licensing deals average $433M in upfront payments with $3.9B total deal value. The 11/89 upfront/milestone split reflects the risk profile at this clinical stage.
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