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ATTR Amyloidosis — Deal Benchmarks & Valuation

Median Upfront
$670M
Range: $368M - $961M
Total Deal Value
$3.2B
Range: $2.1B - $4.3B
Royalty Rate
14.5% - 26.5%
Tiered up to 30.5%
Dev Milestones
$451M
Range: $305M - $599M

Market Analysis

ATTR Amyloidosis is one of the most actively transacted indications in metabolic licensing. Phase 2 deals for attr amyloidosis carry a median total deal value of $3.2B, with upfront payments ranging from $368M to $961M. The recommended deal structure allocates approximately 21% to upfront payments and 79% to milestones.

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Frequently Asked Questions

What are typical deal terms for attr amyloidosis licensing?
Phase 2 attr amyloidosis licensing deals average $670M in upfront payments with $3.2B total deal value. The 21/79 upfront/milestone split reflects the risk profile at this clinical stage.
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