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Diabetic Macular Edema — Deal Benchmarks & Valuation

Median Upfront
$737M
Range: $406M - $1.1B
Total Deal Value
$3.5B
Range: $2.3B - $4.7B
Royalty Rate
10.1% - 20.2%
Tiered up to 24.2%
Dev Milestones
$546M
Range: $370M - $726M

Market Analysis

Diabetic Macular Edema is one of the most actively transacted indications in ophthalmology licensing. Phase 2 deals for diabetic macular edema carry a median total deal value of $3.5B, with upfront payments ranging from $406M to $1.1B. The recommended deal structure allocates approximately 21% to upfront payments and 79% to milestones.

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Frequently Asked Questions

What are typical deal terms for diabetic macular edema licensing?
Phase 2 diabetic macular edema licensing deals average $737M in upfront payments with $3.5B total deal value. The 21/79 upfront/milestone split reflects the risk profile at this clinical stage.
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