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Familial Hypercholesterolemia — Deal Benchmarks & Valuation

Median Upfront
$609M
Range: $334M - $873M
Total Deal Value
$2.9B
Range: $1.9B - $3.9B
Royalty Rate
14.1% - 25.8%
Tiered up to 29.8%
Dev Milestones
$410M
Range: $278M - $544M

Market Analysis

Familial Hypercholesterolemia is one of the most actively transacted indications in metabolic licensing. Phase 2 deals for familial hypercholesterolemia carry a median total deal value of $2.9B, with upfront payments ranging from $334M to $873M. The recommended deal structure allocates approximately 21% to upfront payments and 79% to milestones.

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Frequently Asked Questions

What are typical deal terms for familial hypercholesterolemia licensing?
Phase 2 familial hypercholesterolemia licensing deals average $609M in upfront payments with $2.9B total deal value. The 21/79 upfront/milestone split reflects the risk profile at this clinical stage.
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