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Myelofibrosis — Deal Benchmarks & Valuation

Median Upfront
$636M
Range: $333M - $932M
Total Deal Value
$3.1B
Range: $1.9B - $4.3B
Royalty Rate
8.7% - 16.3%
Tiered up to 20.3%
Dev Milestones
$526M
Range: $339M - $715M

Market Analysis

Myelofibrosis is one of the most actively transacted indications in hematology licensing. Phase 2 deals for myelofibrosis carry a median total deal value of $3.1B, with upfront payments ranging from $333M to $932M. The recommended deal structure allocates approximately 20% to upfront payments and 80% to milestones.

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Frequently Asked Questions

What are typical deal terms for myelofibrosis licensing?
Phase 2 myelofibrosis licensing deals average $636M in upfront payments with $3.1B total deal value. The 20/80 upfront/milestone split reflects the risk profile at this clinical stage.
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