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Oncology vs Ophthalmology — Deal Terms Comparison

Oncology Median Upfront
$258M
Total: $1.6B
Ophthalmology Median Upfront
$768M
Total: $3.6B
Oncology Royalties
11.8%-19.3%
Tiered to 23.3%
Ophthalmology Royalties
10.2%-20.4%
Tiered to 24.4%

Market Analysis

Oncology and Ophthalmology represent distinct licensing landscapes with different risk-reward dynamics. Phase 2 oncology deals carry a median total deal value of $1.6B with $258M upfront, compared to $3.6B total value and $768M upfront for ophthalmology. The differences reflect divergent clinical development timelines, regulatory pathways, and addressable market sizes.

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Frequently Asked Questions

How do oncology and ophthalmology deal terms compare?
Oncology Phase 2 deals average $1.6B total value ($258M upfront), while Ophthalmology deals average $3.6B ($768M upfront). The differences are driven by addressable market size, clinical development complexity, and regulatory pathway characteristics.
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