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Pompe Disease — Deal Benchmarks & Valuation

Median Upfront
$249M
Range: $116M - $383M
Total Deal Value
$2.0B
Range: $1.1B - $2.8B
Royalty Rate
9.5% - 17.8%
Tiered up to 21.8%
Dev Milestones
$514M
Range: $289M - $739M

Market Analysis

Pompe Disease is one of the most actively transacted indications in metabolic licensing. Phase 1 deals for pompe disease carry a median total deal value of $2.0B, with upfront payments ranging from $116M to $383M. The recommended deal structure allocates approximately 13% to upfront payments and 87% to milestones.

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Frequently Asked Questions

What are typical deal terms for pompe disease licensing?
Phase 1 pompe disease licensing deals average $249M in upfront payments with $2.0B total deal value. The 13/87 upfront/milestone split reflects the risk profile at this clinical stage.
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