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Addiction / Substance Use Disorders — Deal Benchmarks & Valuation

Median Upfront
$283M
Range: $141M - $428M
Total Deal Value
$2.5B
Range: $1.5B - $3.5B
Royalty Rate
11.7% - 18.7%
Tiered up to 22.7%
Dev Milestones
$734M
Range: $450M - $1.0B

Market Analysis

Addiction / Substance Use Disorders is one of the most actively transacted indications in neurology licensing. Phase 2 deals for addiction / substance use disorders carry a median total deal value of $2.5B, with upfront payments ranging from $141M to $428M. The recommended deal structure allocates approximately 11% to upfront payments and 89% to milestones.

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Frequently Asked Questions

What are typical deal terms for addiction / substance use disorders licensing?
Phase 2 addiction / substance use disorders licensing deals average $283M in upfront payments with $2.5B total deal value. The 11/89 upfront/milestone split reflects the risk profile at this clinical stage.
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