Metabolic/Obesity Phase 1 Deal Benchmarks — Ex-US (2026)
Median upfront of $103M with total deal values reaching $1.2B in Ex-US territory.
Median Upfront
$103M
Total Deal Value
$807M
Royalty Range
7.3%–13.7%
Territory Multiplier
0.45x
Understanding Metabolic/Obesity Deal Benchmarks at Phase 1
Phase 1 Metabolic/Obesity licensing deals in Ex-US territory command a median upfront payment of $103M, with values ranging from $48M at the low end to $158M for premium assets. These benchmarks reflect the risk-adjusted value of clinical-stage assets in the metabolic/obesity therapeutic area, where development costs, competitive dynamics, and market potential all factor into deal pricing.
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Frequently Asked Questions
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Related Benchmarks
$35M upfront
Metabolic/Obesity · Preclinical · Ex-US
$265M upfront
Metabolic/Obesity · Phase 2 · Ex-US
$554M upfront
Metabolic/Obesity · Phase 3 · Ex-US
$1.6B upfront
Metabolic/Obesity · Approved · Ex-US
$40M upfront
Oncology · Phase 1 · Ex-US
$34M upfront
Neurology/CNS · Phase 1 · Ex-US
$74M upfront
Immunology · Phase 1 · Ex-US
$229M upfront
Metabolic/Obesity · Phase 1 · Global
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Ambrosia Ventures. (2026). Metabolic/Obesity Phase 1 Deal Benchmarks — Ex-US (2026). Retrieved from https://calculator.ambrosiaventures.co/data/metabolic-phase-1-deals-ex-us
<a href="https://calculator.ambrosiaventures.co/data/metabolic-phase-1-deals-ex-us">Metabolic/Obesity Phase 1 Deal Benchmarks — Ex-US (2026)</a> — Ambrosia Ventures (2026)
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Data sourced from 1,900+ verified biopharma transactions. Updated monthly.