Skip to main content

Women's Health Phase 1 Deal Benchmarks

Median upfront of $93M with total deal values reaching $1.2B.

Median Upfront

$93M

Total Deal Value

$819M

Royalty Range

5.6%–11.3%

Territory Multiplier

1x

Understanding Women's Health Deal Benchmarks at Phase 1

Phase 1 Women's Health licensing deals command a median upfront payment of $93M, with values ranging from $42M at the low end to $159M for premium assets. These benchmarks reflect the risk-adjusted value of clinical-stage assets in the women's health therapeutic area, where development costs, competitive dynamics, and market potential all factor into deal pricing.

Total deal values — including milestones for development, regulatory, and commercial achievements — range from $450M to $1.2B, with a median of $819M. Royalty rates for women's health assets at this stage typically fall between 5.6% and 11.3% of net sales, reflecting the balance between licensor value contribution and licensee commercialization investment.

The Global territory applies a 1x multiplier to base deal economics. This accounts for market size, regulatory complexity, pricing environment, and competitive landscape differences across geographies. Licensors negotiating global rights should calibrate upfront expectations and milestone structures accordingly.

Full Benchmark Data

MetricLowMedianHigh
Upfront Payment$42M$93M$159M
Total Deal Value$450M$819M$1.2B
Royalty Rate5.6%11.3%

Comparable Deals

YearLicensorLicenseeUpfrontTotal ValueDeal Type
2022Myovant SciencesSumitomo Pharma$3.0B$3.0Bacquisition
2022TherapeuticsMDMayne Pharma$173M$173Macquisition
2022OrganonForendo Pharma$75M$900Moption
2023ObsEvaXOMA/Kissei$55M$350Mlicensing
2023Dare BioscienceBayer$20M$300Mlicensing
2022Evofem BiosciencesN/A (standalone)$0M$80Mlicensing
2023Mayne PharmaN/A (standalone)$0M$350Mlicensing
2024Biora TherapeuticsN/A (standalone)$0M$150Mlicensing
2024FemasysN/A (standalone)$0M$60Mlicensing
2023Sage TherapeuticsBiogen$875M$1.5Bcollaboration

Frequently Asked Questions

What is the average upfront payment for Phase 1 Women's Health deals?
The median upfront payment for Phase 1 Women's Health licensing deals is $93M, based on our analysis of comparable transactions. Values range from $42M for early-stage or less differentiated assets up to $159M for premium programs with strong clinical data or first-in-class mechanisms.
How does Global territory affect Women's Health deal value?
Global rights carry a 1x multiplier relative to base deal economics. This means global women's health deals are valued at a discount compared to single-country rights, reflecting the combined market opportunity, regulatory pathway, and competitive dynamics of the territory.
What royalty rates are typical for Phase 1 Women's Health licensing?
Royalty rates for Phase 1 women's health assets typically range from 5.6% to 11.3% of net sales. The exact rate depends on the licensor's contribution (IP, clinical data, manufacturing), deal structure (exclusive vs. co-exclusive), and the licensee's commercialization investment. Higher royalties often correspond to lower upfront payments, and vice versa.

Run Your Own Benchmark

These benchmarks are starting points. Get a customized valuation for your specific asset, indication, and deal structure.

Open Deal Calculator

Cite This Data

APA

Ambrosia Ventures. (2026). Women's Health Phase 1 Deal Benchmarks. Retrieved from https://calculator.ambrosiaventures.co/data/womens-health-phase-1-deals-global

HTML

<a href="https://calculator.ambrosiaventures.co/data/womens-health-phase-1-deals-global">Women's Health Phase 1 Deal Benchmarks</a> — Ambrosia Ventures (2026)

Embed Chart

<iframe src="https://calculator.ambrosiaventures.co/api/embed/chart?type=phase-upfront&ta=womensHealth&theme=light" width="600" height="400" frameborder="0" style="border:1px solid #e2e8f0;border-radius:12px;"></iframe>

Data sourced from 2,600+ verified biopharma transactions. Updated monthly.