Skip to main content

Women's Health Phase 2 Deal Benchmarks — Ex-US

Median upfront of $147M with total deal values reaching $1.1B in Ex-US territory.

Median Upfront

$147M

Total Deal Value

$804M

Royalty Range

6.2%–12.4%

Territory Multiplier

0.45x

Understanding Women's Health Deal Benchmarks at Phase 2

Phase 2 Women's Health licensing deals in Ex-US territory command a median upfront payment of $147M, with values ranging from $76M at the low end to $238M for premium assets. These benchmarks reflect the risk-adjusted value of clinical-stage assets in the women's health therapeutic area, where development costs, competitive dynamics, and market potential all factor into deal pricing.

Total deal values — including milestones for development, regulatory, and commercial achievements — range from $498M to $1.1B, with a median of $804M. Royalty rates for women's health assets at this stage typically fall between 6.2% and 12.4% of net sales, reflecting the balance between licensor value contribution and licensee commercialization investment.

The Ex-US territory applies a 0.45x multiplier to base deal economics. This accounts for market size, regulatory complexity, pricing environment, and competitive landscape differences across geographies. Licensors negotiating ex-us rights should calibrate upfront expectations and milestone structures accordingly.

Full Benchmark Data

MetricLowMedianHigh
Upfront Payment$76M$147M$238M
Total Deal Value$498M$804M$1.1B
Royalty Rate6.2%12.4%

Comparable Deals

No territory-specific comparable deals. Use the calculator for full analysis.

Frequently Asked Questions

What is the average upfront payment for Phase 2 Women's Health deals in Ex-US territory?
The median upfront payment for Phase 2 Women's Health licensing deals in Ex-US territory is $147M, based on our analysis of comparable transactions. Values range from $76M for early-stage or less differentiated assets up to $238M for premium programs with strong clinical data or first-in-class mechanisms.
How does Ex-US territory affect Women's Health deal value?
Ex-US rights carry a 0.45x multiplier relative to base deal economics. This means ex-us women's health deals are valued at a discount compared to single-country rights, reflecting the combined market opportunity, regulatory pathway, and competitive dynamics of the territory.
What royalty rates are typical for Phase 2 Women's Health licensing?
Royalty rates for Phase 2 women's health assets typically range from 6.2% to 12.4% of net sales. The exact rate depends on the licensor's contribution (IP, clinical data, manufacturing), deal structure (exclusive vs. co-exclusive), and the licensee's commercialization investment. Higher royalties often correspond to lower upfront payments, and vice versa.

Run Your Own Benchmark

These benchmarks are starting points. Get a customized valuation for your specific asset, indication, and deal structure.

Open Deal Calculator

Cite This Data

APA

Ambrosia Ventures. (2026). Women's Health Phase 2 Deal Benchmarks — Ex-US. Retrieved from https://calculator.ambrosiaventures.co/data/womens-health-phase-2-deals-ex-us

HTML

<a href="https://calculator.ambrosiaventures.co/data/womens-health-phase-2-deals-ex-us">Women's Health Phase 2 Deal Benchmarks — Ex-US</a> — Ambrosia Ventures (2026)

Embed Chart

<iframe src="https://calculator.ambrosiaventures.co/api/embed/chart?type=phase-upfront&ta=womensHealth&theme=light" width="600" height="400" frameborder="0" style="border:1px solid #e2e8f0;border-radius:12px;"></iframe>

Data sourced from 2,600+ verified biopharma transactions. Updated monthly.