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Fabry Disease — Deal Benchmarks & Valuation

Median Upfront
$432M
Range: $212M - $651M
Total Deal Value
$2.3B
Range: $1.4B - $3.3B
Royalty Rate
7.8% - 15.6%
Tiered up to 19.6%
Dev Milestones
$417M
Range: $251M - $584M

Market Analysis

Fabry Disease is one of the most actively transacted indications in rare disease licensing. Phase 2 deals for fabry disease carry a median total deal value of $2.3B, with upfront payments ranging from $212M to $651M. The recommended deal structure allocates approximately 19% to upfront payments and 81% to milestones.

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Frequently Asked Questions

What are typical deal terms for fabry disease licensing?
Phase 2 fabry disease licensing deals average $432M in upfront payments with $2.3B total deal value. The 19/81 upfront/milestone split reflects the risk profile at this clinical stage.
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