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Fragile X Syndrome — Deal Benchmarks & Valuation

Median Upfront
$393M
Range: $192M - $592M
Total Deal Value
$2.1B
Range: $1.2B - $3.0B
Royalty Rate
7.6% - 15.1%
Tiered up to 19.1%
Dev Milestones
$379M
Range: $228M - $531M

Market Analysis

Fragile X Syndrome is one of the most actively transacted indications in rare disease licensing. Phase 2 deals for fragile x syndrome carry a median total deal value of $2.1B, with upfront payments ranging from $192M to $592M. The recommended deal structure allocates approximately 19% to upfront payments and 81% to milestones.

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Frequently Asked Questions

What are typical deal terms for fragile x syndrome licensing?
Phase 2 fragile x syndrome licensing deals average $393M in upfront payments with $2.1B total deal value. The 19/81 upfront/milestone split reflects the risk profile at this clinical stage.
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