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Graft-vs-Host Disease (GVHD) — Deal Benchmarks & Valuation

Median Upfront
$355M
Range: $160M - $560M
Total Deal Value
$3.5B
Range: $1.9B - $5.0B
Royalty Rate
11.8% - 20.6%
Tiered up to 24.6%
Dev Milestones
$1.1B
Range: $609M - $1.6B

Market Analysis

Graft-vs-Host Disease (GVHD) is one of the most actively transacted indications in immunology licensing. Phase 1 deals for graft-vs-host disease (gvhd) carry a median total deal value of $3.5B, with upfront payments ranging from $160M to $560M. The recommended deal structure allocates approximately 10% to upfront payments and 90% to milestones.

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Frequently Asked Questions

What are typical deal terms for graft-vs-host disease (gvhd) licensing?
Phase 1 graft-vs-host disease (gvhd) licensing deals average $355M in upfront payments with $3.5B total deal value. The 10/90 upfront/milestone split reflects the risk profile at this clinical stage.
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