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Hemophilia B — Deal Benchmarks & Valuation

Median Upfront
$326M
Range: $158M - $496M
Total Deal Value
$1.8B
Range: $1.0B - $2.6B
Royalty Rate
8.1% - 16.3%
Tiered up to 20.3%
Dev Milestones
$325M
Range: $195M - $453M

Market Analysis

Hemophilia B is one of the most actively transacted indications in rare disease licensing. Phase 2 deals for hemophilia b carry a median total deal value of $1.8B, with upfront payments ranging from $158M to $496M. The recommended deal structure allocates approximately 18% to upfront payments and 82% to milestones.

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Frequently Asked Questions

What are typical deal terms for hemophilia b licensing?
Phase 2 hemophilia b licensing deals average $326M in upfront payments with $1.8B total deal value. The 18/82 upfront/milestone split reflects the risk profile at this clinical stage.
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