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Pompe Disease — Deal Benchmarks & Valuation

Median Upfront
$421M
Range: $206M - $635M
Total Deal Value
$2.3B
Range: $1.3B - $3.2B
Royalty Rate
7.7% - 15.5%
Tiered up to 19.5%
Dev Milestones
$406M
Range: $244M - $569M

Market Analysis

Pompe Disease is one of the most actively transacted indications in rare disease licensing. Phase 2 deals for pompe disease carry a median total deal value of $2.3B, with upfront payments ranging from $206M to $635M. The recommended deal structure allocates approximately 19% to upfront payments and 81% to milestones.

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Frequently Asked Questions

What are typical deal terms for pompe disease licensing?
Phase 2 pompe disease licensing deals average $421M in upfront payments with $2.3B total deal value. The 19/81 upfront/milestone split reflects the risk profile at this clinical stage.
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