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2026 Market Data

Biopharma Deal Benchmarks

Data-driven licensing deal term analysis across oncology, neurology, and all major modalities. Upfronts, milestones, royalties, and deal structures.

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Market Overviews

Comprehensive 2026 deal landscape analysis across oncology, neurology, immunology, and metabolic/obesity therapeutic areas.

Oncology Licensing Deal Benchmarks 2026

Comprehensive 2026 oncology licensing deal benchmarks across ADCs, CAR-T, bispecifics, and all clinical stages. Data-driven analysis of upfronts, milestones, and royalties.

Phase 2 ADC (Median): $2.6BPhase 1 CAR-T (Median): $1.0B
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Neurology & CNS Licensing Deal Benchmarks 2026

Comprehensive 2026 neurology and CNS licensing deal benchmarks. Alzheimer's, Parkinson's, pain, and psychiatric disorder deal terms analyzed.

Alzheimer's (Phase 2): $3.5BParkinson's (Phase 2): $3.1B
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Metabolic & Obesity Deal Benchmarks 2026

Comprehensive 2026 metabolic and obesity licensing deal benchmarks. GLP-1 agonists, dual incretins, oral peptides, and MASH deal terms analyzed from 35+ R&D partnerships.

Median Upfront: $935MTotal Deal Value: $4.5B
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Rare Disease Licensing Deal Benchmarks 2026

Rare disease licensing deals average $2.2B total value at Phase 2 with orphan drug designation. Benchmark upfronts, milestones, and royalties across gene therapy, ERT, and substrate reduction.

Gene Therapy (Phase 2): $2.2BERT (Phase 2): $2.3B
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Hematology Licensing Deal Benchmarks 2026

Comprehensive 2026 hematology licensing benchmarks. CAR-T, bispecific antibody, and small molecule deal terms across lymphoma, leukemia, and myeloproliferative neoplasms.

CAR-T DLBCL (Phase 1): $2.1BBispecific AML (Phase 2): $3.7B
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Dermatology Licensing Deal Benchmarks 2026

Comprehensive 2026 dermatology licensing benchmarks. IL-17, IL-13, JAK inhibitor, and topical biologic deal terms across atopic dermatitis, psoriasis, and emerging indications.

IL-13 AD (Phase 2): $2.4BIL-17 Psoriasis (Phase 2): $2.1B
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Gastroenterology Licensing Deal Benchmarks 2026

Comprehensive 2026 gastroenterology licensing benchmarks. Anti-TL1A, IL-23, and S1P modulator deal terms across Crohn's disease, ulcerative colitis, and emerging GI indications.

Anti-TL1A Crohn's (Phase 2): $3.3BIL-23 UC (Phase 2): $3.0B
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Immunology & Autoimmune Deal Benchmarks 2026

Immunology licensing deals average $3.0B total value at Phase 2. Benchmark autoimmune deal terms for lupus, JAK inhibitors, and biologics.

Median Upfront: $575MTotal Deal Value: $3.0B
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Cardiovascular Deal Benchmarks 2026

Cardiovascular licensing deals average $2.4B total value at Phase 2. Benchmark CV deal terms for heart failure, PCSK9, and lipid therapies.

Median Upfront: $480MTotal Deal Value: $2.4B
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Infectious Disease Deal Benchmarks 2026

Infectious disease licensing deals average $1.9B total value at Phase 2. Benchmark antiviral, antibiotic, and vaccine deal terms.

Median Upfront: $488MTotal Deal Value: $1.9B
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Ophthalmology Deal Benchmarks 2026

Ophthalmology licensing deals average $2.5B total value at Phase 2. Benchmark gene therapy, anti-VEGF, and retinal deal terms.

Median Upfront: $522MTotal Deal Value: $2.5B
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ADC vs. Bispecific Antibody Deal Terms Comparison

Compare ADC vs bispecific antibody deal terms: ADC median upfront $393M vs bispecific $348M. Side-by-side benchmarks.

ADC Median Upfront: $393MBispecific Median Upfront: $348M
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Phase 1 vs. Phase 2 Deal Valuation Comparison

Compare Phase 1 vs Phase 2 deal terms: Phase 1 upfront $90M vs Phase 2 $258M. Data-driven stage comparison.

Phase 1 Median Upfront: $90MPhase 2 Median Upfront: $258M
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Oncology vs. Neurology Licensing Deal Comparison

Compare oncology vs neurology deal terms: oncology upfront $258M vs neurology $423M. TA-specific benchmarks.

Oncology Median Upfront: $258MNeurology Median Upfront: $423M
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ADC vs Bispecific Antibody — Oncology Deal Terms Comparison

Compare adc vs bispecific antibody deal terms in oncology: ADC median upfront $411M vs Bispecific Antibody $348M. Side-by-side benchmarks from 2,500+ deals.

ADC Median Upfront: $411MBispecific Antibody Median Upfront: $348M
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Small Molecule vs Monoclonal Antibody — Oncology Deal Terms Comparison

Compare small molecule vs monoclonal antibody deal terms in oncology: Small Molecule median upfront $258M vs Monoclonal Antibody $266M. Side-by-side benchmarks from 2,500+ deals.

Small Molecule Median Upfront: $258MMonoclonal Antibody Median Upfront: $266M
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ADC vs CAR-T (Heme) — Oncology Deal Terms Comparison

Compare adc vs car-t (heme) deal terms in oncology: ADC median upfront $411M vs CAR-T (Heme) $309M. Side-by-side benchmarks from 2,500+ deals.

ADC Median Upfront: $411MCAR-T (Heme) Median Upfront: $309M
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Small Molecule vs ADC — Oncology Deal Terms Comparison

Compare small molecule vs adc deal terms in oncology: Small Molecule median upfront $258M vs ADC $411M. Side-by-side benchmarks from 2,500+ deals.

Small Molecule Median Upfront: $258MADC Median Upfront: $411M
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Bispecific Antibody vs CAR-T (Heme) — Oncology Deal Terms Comparison

Compare bispecific antibody vs car-t (heme) deal terms in oncology: Bispecific Antibody median upfront $348M vs CAR-T (Heme) $309M. Side-by-side benchmarks from 2,500+ deals.

Bispecific Antibody Median Upfront: $348MCAR-T (Heme) Median Upfront: $309M
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Radiopharmaceutical vs ADC — Oncology Deal Terms Comparison

Compare radiopharmaceutical vs adc deal terms in oncology: Radiopharmaceutical median upfront $407M vs ADC $411M. Side-by-side benchmarks from 2,500+ deals.

Radiopharmaceutical Median Upfront: $407MADC Median Upfront: $411M
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PROTAC vs Small Molecule — Oncology Deal Terms Comparison

Compare protac vs small molecule deal terms in oncology: PROTAC median upfront $348M vs Small Molecule $258M. Side-by-side benchmarks from 2,500+ deals.

PROTAC Median Upfront: $348MSmall Molecule Median Upfront: $258M
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Monoclonal Antibody vs Bispecific Antibody — Oncology Deal Terms Comparison

Compare monoclonal antibody vs bispecific antibody deal terms in oncology: Monoclonal Antibody median upfront $266M vs Bispecific Antibody $348M. Side-by-side benchmarks from 2,500+ deals.

Monoclonal Antibody Median Upfront: $266MBispecific Antibody Median Upfront: $348M
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Gene Therapy vs CAR-T (Solid Tumor) — Oncology Deal Terms Comparison

Compare gene therapy vs car-t (solid tumor) deal terms in oncology: Gene Therapy median upfront $253M vs CAR-T (Solid Tumor) $356M. Side-by-side benchmarks from 2,500+ deals.

Gene Therapy Median Upfront: $253MCAR-T (Solid Tumor) Median Upfront: $356M
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RNAi / siRNA vs ASO — Oncology Deal Terms Comparison

Compare rnai / sirna vs aso deal terms in oncology: RNAi / siRNA median upfront $297M vs ASO $297M. Side-by-side benchmarks from 2,500+ deals.

RNAi / siRNA Median Upfront: $297MASO Median Upfront: $297M
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Therapeutic Vaccine vs Monoclonal Antibody — Oncology Deal Terms Comparison

Compare therapeutic vaccine vs monoclonal antibody deal terms in oncology: Therapeutic Vaccine median upfront $297M vs Monoclonal Antibody $266M. Side-by-side benchmarks from 2,500+ deals.

Therapeutic Vaccine Median Upfront: $297MMonoclonal Antibody Median Upfront: $266M
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Molecular Glue vs PROTAC — Oncology Deal Terms Comparison

Compare molecular glue vs protac deal terms in oncology: Molecular Glue median upfront $361M vs PROTAC $348M. Side-by-side benchmarks from 2,500+ deals.

Molecular Glue Median Upfront: $361MPROTAC Median Upfront: $348M
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ADC vs Radiopharmaceutical — Oncology Deal Terms Comparison

Compare adc vs radiopharmaceutical deal terms in oncology: ADC median upfront $411M vs Radiopharmaceutical $407M. Side-by-side benchmarks from 2,500+ deals.

ADC Median Upfront: $411MRadiopharmaceutical Median Upfront: $407M
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CAR-T (Heme) vs CAR-T (Solid Tumor) — Oncology Deal Terms Comparison

Compare car-t (heme) vs car-t (solid tumor) deal terms in oncology: CAR-T (Heme) median upfront $309M vs CAR-T (Solid Tumor) $356M. Side-by-side benchmarks from 2,500+ deals.

CAR-T (Heme) Median Upfront: $309MCAR-T (Solid Tumor) Median Upfront: $356M
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Monoclonal Antibody vs ADC — Oncology Deal Terms Comparison

Compare monoclonal antibody vs adc deal terms in oncology: Monoclonal Antibody median upfront $266M vs ADC $411M. Side-by-side benchmarks from 2,500+ deals.

Monoclonal Antibody Median Upfront: $266MADC Median Upfront: $411M
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Bispecific Antibody vs T-Cell Engager — Oncology Deal Terms Comparison

Compare bispecific antibody vs t-cell engager deal terms in oncology: Bispecific Antibody median upfront $348M vs T-Cell Engager $335M. Side-by-side benchmarks from 2,500+ deals.

Bispecific Antibody Median Upfront: $348MT-Cell Engager Median Upfront: $335M
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Small Molecule vs PROTAC — Oncology Deal Terms Comparison

Compare small molecule vs protac deal terms in oncology: Small Molecule median upfront $258M vs PROTAC $348M. Side-by-side benchmarks from 2,500+ deals.

Small Molecule Median Upfront: $258MPROTAC Median Upfront: $348M
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Oncolytic Virus vs Therapeutic Vaccine — Oncology Deal Terms Comparison

Compare oncolytic virus vs therapeutic vaccine deal terms in oncology: Oncolytic Virus median upfront $280M vs Therapeutic Vaccine $297M. Side-by-side benchmarks from 2,500+ deals.

Oncolytic Virus Median Upfront: $280MTherapeutic Vaccine Median Upfront: $297M
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mRNA vs Therapeutic Vaccine — Oncology Deal Terms Comparison

Compare mrna vs therapeutic vaccine deal terms in oncology: mRNA median upfront $335M vs Therapeutic Vaccine $297M. Side-by-side benchmarks from 2,500+ deals.

mRNA Median Upfront: $335MTherapeutic Vaccine Median Upfront: $297M
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Peptide vs Small Molecule — Oncology Deal Terms Comparison

Compare peptide vs small molecule deal terms in oncology: Peptide median upfront $271M vs Small Molecule $258M. Side-by-side benchmarks from 2,500+ deals.

Peptide Median Upfront: $271MSmall Molecule Median Upfront: $258M
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Small Molecule vs Monoclonal Antibody — Neurology Deal Terms Comparison

Compare small molecule vs monoclonal antibody deal terms in neurology: Small Molecule median upfront $343M vs Monoclonal Antibody $354M. Side-by-side benchmarks from 2,500+ deals.

Small Molecule Median Upfront: $343MMonoclonal Antibody Median Upfront: $354M
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ASO vs Gene Therapy — Neurology Deal Terms Comparison

Compare aso vs gene therapy deal terms in neurology: ASO median upfront $389M vs Gene Therapy $331M. Side-by-side benchmarks from 2,500+ deals.

ASO Median Upfront: $389MGene Therapy Median Upfront: $331M
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Small Molecule vs BBB Platform — Neurology Deal Terms Comparison

Compare small molecule vs bbb platform deal terms in neurology: Small Molecule median upfront $343M vs BBB Platform $558M. Side-by-side benchmarks from 2,500+ deals.

Small Molecule Median Upfront: $343MBBB Platform Median Upfront: $558M
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Monoclonal Antibody vs Gene Therapy — Neurology Deal Terms Comparison

Compare monoclonal antibody vs gene therapy deal terms in neurology: Monoclonal Antibody median upfront $354M vs Gene Therapy $331M. Side-by-side benchmarks from 2,500+ deals.

Monoclonal Antibody Median Upfront: $354MGene Therapy Median Upfront: $331M
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Psychedelic vs Small Molecule — Neurology Deal Terms Comparison

Compare psychedelic vs small molecule deal terms in neurology: Psychedelic median upfront $378M vs Small Molecule $343M. Side-by-side benchmarks from 2,500+ deals.

Psychedelic Median Upfront: $378MSmall Molecule Median Upfront: $343M
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Ion Channel vs Small Molecule — Neurology Deal Terms Comparison

Compare ion channel vs small molecule deal terms in neurology: Ion Channel median upfront $378M vs Small Molecule $343M. Side-by-side benchmarks from 2,500+ deals.

Ion Channel Median Upfront: $378MSmall Molecule Median Upfront: $343M
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Tau-Targeting vs Monoclonal Antibody — Neurology Deal Terms Comparison

Compare tau-targeting vs monoclonal antibody deal terms in neurology: Tau-Targeting median upfront $464M vs Monoclonal Antibody $354M. Side-by-side benchmarks from 2,500+ deals.

Tau-Targeting Median Upfront: $464MMonoclonal Antibody Median Upfront: $354M
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ASO vs RNAi / siRNA — Neurology Deal Terms Comparison

Compare aso vs rnai / sirna deal terms in neurology: ASO median upfront $389M vs RNAi / siRNA $395M. Side-by-side benchmarks from 2,500+ deals.

ASO Median Upfront: $389MRNAi / siRNA Median Upfront: $395M
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Stem Cell vs Gene Therapy — Neurology Deal Terms Comparison

Compare stem cell vs gene therapy deal terms in neurology: Stem Cell median upfront $395M vs Gene Therapy $331M. Side-by-side benchmarks from 2,500+ deals.

Stem Cell Median Upfront: $395MGene Therapy Median Upfront: $331M
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Small Molecule vs ASO — Neurology Deal Terms Comparison

Compare small molecule vs aso deal terms in neurology: Small Molecule median upfront $343M vs ASO $389M. Side-by-side benchmarks from 2,500+ deals.

Small Molecule Median Upfront: $343MASO Median Upfront: $389M
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BBB Platform vs Gene Therapy — Neurology Deal Terms Comparison

Compare bbb platform vs gene therapy deal terms in neurology: BBB Platform median upfront $558M vs Gene Therapy $331M. Side-by-side benchmarks from 2,500+ deals.

BBB Platform Median Upfront: $558MGene Therapy Median Upfront: $331M
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Peptide vs Monoclonal Antibody — Neurology Deal Terms Comparison

Compare peptide vs monoclonal antibody deal terms in neurology: Peptide median upfront $361M vs Monoclonal Antibody $354M. Side-by-side benchmarks from 2,500+ deals.

Peptide Median Upfront: $361MMonoclonal Antibody Median Upfront: $354M
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Small Molecule vs Psychedelic — Neurology Deal Terms Comparison

Compare small molecule vs psychedelic deal terms in neurology: Small Molecule median upfront $343M vs Psychedelic $378M. Side-by-side benchmarks from 2,500+ deals.

Small Molecule Median Upfront: $343MPsychedelic Median Upfront: $378M
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Monoclonal Antibody vs ASO — Neurology Deal Terms Comparison

Compare monoclonal antibody vs aso deal terms in neurology: Monoclonal Antibody median upfront $354M vs ASO $389M. Side-by-side benchmarks from 2,500+ deals.

Monoclonal Antibody Median Upfront: $354MASO Median Upfront: $389M
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Gene Therapy vs RNAi / siRNA — Neurology Deal Terms Comparison

Compare gene therapy vs rnai / sirna deal terms in neurology: Gene Therapy median upfront $331M vs RNAi / siRNA $395M. Side-by-side benchmarks from 2,500+ deals.

Gene Therapy Median Upfront: $331MRNAi / siRNA Median Upfront: $395M
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JAK Inhibitor vs TL1A Inhibitor — Immunology Deal Terms Comparison

Compare jak inhibitor vs tl1a inhibitor deal terms in immunology: JAK Inhibitor median upfront $513M vs TL1A Inhibitor $676M. Side-by-side benchmarks from 2,500+ deals.

JAK Inhibitor Median Upfront: $513MTL1A Inhibitor Median Upfront: $676M
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Monoclonal Antibody vs Bispecific Antibody — Immunology Deal Terms Comparison

Compare monoclonal antibody vs bispecific antibody deal terms in immunology: Monoclonal Antibody median upfront $480M vs Bispecific Antibody $629M. Side-by-side benchmarks from 2,500+ deals.

Monoclonal Antibody Median Upfront: $480MBispecific Antibody Median Upfront: $629M
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CAR-T (Autoimmune) vs Monoclonal Antibody — Immunology Deal Terms Comparison

Compare car-t (autoimmune) vs monoclonal antibody deal terms in immunology: CAR-T (Autoimmune) median upfront $914M vs Monoclonal Antibody $480M. Side-by-side benchmarks from 2,500+ deals.

CAR-T (Autoimmune) Median Upfront: $914MMonoclonal Antibody Median Upfront: $480M
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FcRn Antagonist vs Complement Inhibitor — Immunology Deal Terms Comparison

Compare fcrn antagonist vs complement inhibitor deal terms in immunology: FcRn Antagonist median upfront $583M vs Complement Inhibitor $560M. Side-by-side benchmarks from 2,500+ deals.

FcRn Antagonist Median Upfront: $583MComplement Inhibitor Median Upfront: $560M
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Small Molecule vs Monoclonal Antibody — Immunology Deal Terms Comparison

Compare small molecule vs monoclonal antibody deal terms in immunology: Small Molecule median upfront $466M vs Monoclonal Antibody $480M. Side-by-side benchmarks from 2,500+ deals.

Small Molecule Median Upfront: $466MMonoclonal Antibody Median Upfront: $480M
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JAK Inhibitor vs Monoclonal Antibody — Immunology Deal Terms Comparison

Compare jak inhibitor vs monoclonal antibody deal terms in immunology: JAK Inhibitor median upfront $513M vs Monoclonal Antibody $480M. Side-by-side benchmarks from 2,500+ deals.

JAK Inhibitor Median Upfront: $513MMonoclonal Antibody Median Upfront: $480M
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S1P Modulator vs JAK Inhibitor — Immunology Deal Terms Comparison

Compare s1p modulator vs jak inhibitor deal terms in immunology: S1P Modulator median upfront $536M vs JAK Inhibitor $513M. Side-by-side benchmarks from 2,500+ deals.

S1P Modulator Median Upfront: $536MJAK Inhibitor Median Upfront: $513M
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Oral Integrin vs TL1A Inhibitor — Immunology Deal Terms Comparison

Compare oral integrin vs tl1a inhibitor deal terms in immunology: Oral Integrin median upfront $629M vs TL1A Inhibitor $676M. Side-by-side benchmarks from 2,500+ deals.

Oral Integrin Median Upfront: $629MTL1A Inhibitor Median Upfront: $676M
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CAR-T (Autoimmune) vs CAR-Treg — Immunology Deal Terms Comparison

Compare car-t (autoimmune) vs car-treg deal terms in immunology: CAR-T (Autoimmune) median upfront $914M vs CAR-Treg $767M. Side-by-side benchmarks from 2,500+ deals.

CAR-T (Autoimmune) Median Upfront: $914MCAR-Treg Median Upfront: $767M
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Bispecific Antibody vs FcRn Antagonist — Immunology Deal Terms Comparison

Compare bispecific antibody vs fcrn antagonist deal terms in immunology: Bispecific Antibody median upfront $629M vs FcRn Antagonist $583M. Side-by-side benchmarks from 2,500+ deals.

Bispecific Antibody Median Upfront: $629MFcRn Antagonist Median Upfront: $583M
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Monoclonal Antibody vs FcRn Antagonist — Immunology Deal Terms Comparison

Compare monoclonal antibody vs fcrn antagonist deal terms in immunology: Monoclonal Antibody median upfront $480M vs FcRn Antagonist $583M. Side-by-side benchmarks from 2,500+ deals.

Monoclonal Antibody Median Upfront: $480MFcRn Antagonist Median Upfront: $583M
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Complement Inhibitor vs Monoclonal Antibody — Immunology Deal Terms Comparison

Compare complement inhibitor vs monoclonal antibody deal terms in immunology: Complement Inhibitor median upfront $560M vs Monoclonal Antibody $480M. Side-by-side benchmarks from 2,500+ deals.

Complement Inhibitor Median Upfront: $560MMonoclonal Antibody Median Upfront: $480M
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Dual Antagonist vs Monoclonal Antibody — Immunology Deal Terms Comparison

Compare dual antagonist vs monoclonal antibody deal terms in immunology: Dual Antagonist median upfront $606M vs Monoclonal Antibody $480M. Side-by-side benchmarks from 2,500+ deals.

Dual Antagonist Median Upfront: $606MMonoclonal Antibody Median Upfront: $480M
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Small Molecule vs JAK Inhibitor — Immunology Deal Terms Comparison

Compare small molecule vs jak inhibitor deal terms in immunology: Small Molecule median upfront $466M vs JAK Inhibitor $513M. Side-by-side benchmarks from 2,500+ deals.

Small Molecule Median Upfront: $466MJAK Inhibitor Median Upfront: $513M
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In Vivo CAR-T vs CAR-T (Autoimmune) — Immunology Deal Terms Comparison

Compare in vivo car-t vs car-t (autoimmune) deal terms in immunology: In Vivo CAR-T median upfront $652M vs CAR-T (Autoimmune) $914M. Side-by-side benchmarks from 2,500+ deals.

In Vivo CAR-T Median Upfront: $652MCAR-T (Autoimmune) Median Upfront: $914M
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GLP-1 Agonist vs Dual Incretin — Metabolic Deal Terms Comparison

Compare glp-1 agonist vs dual incretin deal terms in metabolic: GLP-1 Agonist median upfront $935M vs Dual Incretin $1.2B. Side-by-side benchmarks from 2,500+ deals.

GLP-1 Agonist Median Upfront: $935MDual Incretin Median Upfront: $1.2B
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GLP-1 Agonist vs Oral Peptide — Metabolic Deal Terms Comparison

Compare glp-1 agonist vs oral peptide deal terms in metabolic: GLP-1 Agonist median upfront $935M vs Oral Peptide $1.4B. Side-by-side benchmarks from 2,500+ deals.

GLP-1 Agonist Median Upfront: $935MOral Peptide Median Upfront: $1.4B
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Dual Incretin vs Triple Incretin — Metabolic Deal Terms Comparison

Compare dual incretin vs triple incretin deal terms in metabolic: Dual Incretin median upfront $1.2B vs Triple Incretin $1.2B. Side-by-side benchmarks from 2,500+ deals.

Dual Incretin Median Upfront: $1.2BTriple Incretin Median Upfront: $1.2B
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Small Molecule vs GLP-1 Agonist — Metabolic Deal Terms Comparison

Compare small molecule vs glp-1 agonist deal terms in metabolic: Small Molecule median upfront $683M vs GLP-1 Agonist $935M. Side-by-side benchmarks from 2,500+ deals.

Small Molecule Median Upfront: $683MGLP-1 Agonist Median Upfront: $935M
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SGLT2 Inhibitor vs GLP-1 Agonist — Metabolic Deal Terms Comparison

Compare sglt2 inhibitor vs glp-1 agonist deal terms in metabolic: SGLT2 Inhibitor median upfront $751M vs GLP-1 Agonist $935M. Side-by-side benchmarks from 2,500+ deals.

SGLT2 Inhibitor Median Upfront: $751MGLP-1 Agonist Median Upfront: $935M
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Amylin Analog vs GLP-1 Agonist — Metabolic Deal Terms Comparison

Compare amylin analog vs glp-1 agonist deal terms in metabolic: Amylin Analog median upfront $996M vs GLP-1 Agonist $935M. Side-by-side benchmarks from 2,500+ deals.

Amylin Analog Median Upfront: $996MGLP-1 Agonist Median Upfront: $935M
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Anti-Activin vs GLP-1 Agonist — Metabolic Deal Terms Comparison

Compare anti-activin vs glp-1 agonist deal terms in metabolic: Anti-Activin median upfront $1.0B vs GLP-1 Agonist $935M. Side-by-side benchmarks from 2,500+ deals.

Anti-Activin Median Upfront: $1.0BGLP-1 Agonist Median Upfront: $935M
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Oral Peptide vs Dual Incretin — Metabolic Deal Terms Comparison

Compare oral peptide vs dual incretin deal terms in metabolic: Oral Peptide median upfront $1.4B vs Dual Incretin $1.2B. Side-by-side benchmarks from 2,500+ deals.

Oral Peptide Median Upfront: $1.4BDual Incretin Median Upfront: $1.2B
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Small Molecule vs Dual Incretin — Metabolic Deal Terms Comparison

Compare small molecule vs dual incretin deal terms in metabolic: Small Molecule median upfront $683M vs Dual Incretin $1.2B. Side-by-side benchmarks from 2,500+ deals.

Small Molecule Median Upfront: $683MDual Incretin Median Upfront: $1.2B
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Monoclonal Antibody vs GLP-1 Agonist — Metabolic Deal Terms Comparison

Compare monoclonal antibody vs glp-1 agonist deal terms in metabolic: Monoclonal Antibody median upfront $703M vs GLP-1 Agonist $935M. Side-by-side benchmarks from 2,500+ deals.

Monoclonal Antibody Median Upfront: $703MGLP-1 Agonist Median Upfront: $935M
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Microbiome vs GLP-1 Agonist — Metabolic Deal Terms Comparison

Compare microbiome vs glp-1 agonist deal terms in metabolic: Microbiome median upfront $533M vs GLP-1 Agonist $935M. Side-by-side benchmarks from 2,500+ deals.

Microbiome Median Upfront: $533MGLP-1 Agonist Median Upfront: $935M
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Gene Therapy vs Small Molecule — Metabolic Deal Terms Comparison

Compare gene therapy vs small molecule deal terms in metabolic: Gene Therapy median upfront $669M vs Small Molecule $683M. Side-by-side benchmarks from 2,500+ deals.

Gene Therapy Median Upfront: $669MSmall Molecule Median Upfront: $683M
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Triple Incretin vs Oral Peptide — Metabolic Deal Terms Comparison

Compare triple incretin vs oral peptide deal terms in metabolic: Triple Incretin median upfront $1.2B vs Oral Peptide $1.4B. Side-by-side benchmarks from 2,500+ deals.

Triple Incretin Median Upfront: $1.2BOral Peptide Median Upfront: $1.4B
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Gene Therapy vs ASO — Rare Disease Deal Terms Comparison

Compare gene therapy vs aso deal terms in rare disease: Gene Therapy median upfront $285M vs ASO $456M. Side-by-side benchmarks from 2,500+ deals.

Gene Therapy Median Upfront: $285MASO Median Upfront: $456M
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Gene Therapy vs Small Molecule — Rare Disease Deal Terms Comparison

Compare gene therapy vs small molecule deal terms in rare disease: Gene Therapy median upfront $285M vs Small Molecule $446M. Side-by-side benchmarks from 2,500+ deals.

Gene Therapy Median Upfront: $285MSmall Molecule Median Upfront: $446M
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Monoclonal Antibody vs Small Molecule — Rare Disease Deal Terms Comparison

Compare monoclonal antibody vs small molecule deal terms in rare disease: Monoclonal Antibody median upfront $409M vs Small Molecule $446M. Side-by-side benchmarks from 2,500+ deals.

Monoclonal Antibody Median Upfront: $409MSmall Molecule Median Upfront: $446M
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Cell Therapy vs Gene Therapy — Rare Disease Deal Terms Comparison

Compare cell therapy vs gene therapy deal terms in rare disease: Cell Therapy median upfront $456M vs Gene Therapy $285M. Side-by-side benchmarks from 2,500+ deals.

Cell Therapy Median Upfront: $456MGene Therapy Median Upfront: $285M
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RNAi / siRNA vs ASO — Rare Disease Deal Terms Comparison

Compare rnai / sirna vs aso deal terms in rare disease: RNAi / siRNA median upfront $456M vs ASO $456M. Side-by-side benchmarks from 2,500+ deals.

RNAi / siRNA Median Upfront: $456MASO Median Upfront: $456M
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Gene Therapy vs Cell Therapy — Rare Disease Deal Terms Comparison

Compare gene therapy vs cell therapy deal terms in rare disease: Gene Therapy median upfront $285M vs Cell Therapy $456M. Side-by-side benchmarks from 2,500+ deals.

Gene Therapy Median Upfront: $285MCell Therapy Median Upfront: $456M
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Peptide vs Small Molecule — Rare Disease Deal Terms Comparison

Compare peptide vs small molecule deal terms in rare disease: Peptide median upfront $416M vs Small Molecule $446M. Side-by-side benchmarks from 2,500+ deals.

Peptide Median Upfront: $416MSmall Molecule Median Upfront: $446M
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Preclinical vs Phase 1 — Oncology Deal Valuation Comparison

Compare Preclinical vs Phase 1 deal terms in oncology: Phase 1 commands a 75% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Preclinical Median Upfront: $32MPhase 1 Median Upfront: $90M
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Phase 1 vs Phase 2 — Oncology Deal Valuation Comparison

Compare Phase 1 vs Phase 2 deal terms in oncology: Phase 2 commands a 86% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 1 Median Upfront: $90MPhase 2 Median Upfront: $258M
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Phase 2 vs Phase 3 — Oncology Deal Valuation Comparison

Compare Phase 2 vs Phase 3 deal terms in oncology: Phase 3 commands a 92% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 2 Median Upfront: $258MPhase 3 Median Upfront: $721M
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Phase 3 vs Approved — Oncology Deal Valuation Comparison

Compare Phase 3 vs Approved deal terms in oncology: Approved commands a 80% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 3 Median Upfront: $721MApproved Median Upfront: $2.1B
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Preclinical vs Phase 2 — Oncology Deal Valuation Comparison

Compare Preclinical vs Phase 2 deal terms in oncology: Phase 2 commands a 225% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Preclinical Median Upfront: $32MPhase 2 Median Upfront: $258M
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Preclinical vs Phase 1 — Neurology Deal Valuation Comparison

Compare Preclinical vs Phase 1 deal terms in neurology: Phase 1 commands a 46% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Preclinical Median Upfront: $47MPhase 1 Median Upfront: $112M
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Phase 1 vs Phase 2 — Neurology Deal Valuation Comparison

Compare Phase 1 vs Phase 2 deal terms in neurology: Phase 2 commands a 87% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 1 Median Upfront: $112MPhase 2 Median Upfront: $343M
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Phase 2 vs Phase 3 — Neurology Deal Valuation Comparison

Compare Phase 2 vs Phase 3 deal terms in neurology: Phase 3 commands a 33% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 2 Median Upfront: $343MPhase 3 Median Upfront: $770M
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Phase 3 vs Approved — Neurology Deal Valuation Comparison

Compare Phase 3 vs Approved deal terms in neurology: Approved commands a 75% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 3 Median Upfront: $770MApproved Median Upfront: $2.2B
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Preclinical vs Phase 2 — Neurology Deal Valuation Comparison

Compare Preclinical vs Phase 2 deal terms in neurology: Phase 2 commands a 173% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Preclinical Median Upfront: $47MPhase 2 Median Upfront: $343M
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Preclinical vs Phase 1 — Immunology Deal Valuation Comparison

Compare Preclinical vs Phase 1 deal terms in immunology: Phase 1 commands a 46% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Preclinical Median Upfront: $63MPhase 1 Median Upfront: $144M
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Phase 1 vs Phase 2 — Immunology Deal Valuation Comparison

Compare Phase 1 vs Phase 2 deal terms in immunology: Phase 2 commands a 89% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 1 Median Upfront: $144MPhase 2 Median Upfront: $480M
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Phase 2 vs Phase 3 — Immunology Deal Valuation Comparison

Compare Phase 2 vs Phase 3 deal terms in immunology: Phase 3 commands a 22% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 2 Median Upfront: $480MPhase 3 Median Upfront: $789M
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Phase 3 vs Approved — Immunology Deal Valuation Comparison

Compare Phase 3 vs Approved deal terms in immunology: Approved commands a 150% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 3 Median Upfront: $789MApproved Median Upfront: $3.0B
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Preclinical vs Phase 2 — Immunology Deal Valuation Comparison

Compare Preclinical vs Phase 2 deal terms in immunology: Phase 2 commands a 177% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Preclinical Median Upfront: $63MPhase 2 Median Upfront: $480M
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Preclinical vs Phase 1 — Metabolic Deal Valuation Comparison

Compare Preclinical vs Phase 1 deal terms in metabolic: Phase 1 commands a 83% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Preclinical Median Upfront: $122MPhase 1 Median Upfront: $365M
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Phase 1 vs Phase 2 — Metabolic Deal Valuation Comparison

Compare Phase 1 vs Phase 2 deal terms in metabolic: Phase 2 commands a 55% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 1 Median Upfront: $365MPhase 2 Median Upfront: $935M
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Phase 2 vs Phase 3 — Metabolic Deal Valuation Comparison

Compare Phase 2 vs Phase 3 deal terms in metabolic: Phase 3 commands a 65% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 2 Median Upfront: $935MPhase 3 Median Upfront: $2.0B
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Phase 3 vs Approved — Metabolic Deal Valuation Comparison

Compare Phase 3 vs Approved deal terms in metabolic: Approved commands a 96% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 3 Median Upfront: $2.0BApproved Median Upfront: $5.6B
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Preclinical vs Phase 2 — Metabolic Deal Valuation Comparison

Compare Preclinical vs Phase 2 deal terms in metabolic: Phase 2 commands a 183% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Preclinical Median Upfront: $122MPhase 2 Median Upfront: $935M
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Preclinical vs Phase 1 — Rare Disease Deal Valuation Comparison

Compare Preclinical vs Phase 1 deal terms in rare disease: Phase 1 commands a 70% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Preclinical Median Upfront: $36MPhase 1 Median Upfront: $91M
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Phase 1 vs Phase 2 — Rare Disease Deal Valuation Comparison

Compare Phase 1 vs Phase 2 deal terms in rare disease: Phase 2 commands a 86% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 1 Median Upfront: $91MPhase 2 Median Upfront: $285M
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Phase 2 vs Phase 3 — Rare Disease Deal Valuation Comparison

Compare Phase 2 vs Phase 3 deal terms in rare disease: Phase 3 commands a 114% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 2 Median Upfront: $285MPhase 3 Median Upfront: $971M
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Phase 3 vs Approved — Rare Disease Deal Valuation Comparison

Compare Phase 3 vs Approved deal terms in rare disease: Approved commands a 87% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 3 Median Upfront: $971MApproved Median Upfront: $2.6B
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Preclinical vs Phase 2 — Rare Disease Deal Valuation Comparison

Compare Preclinical vs Phase 2 deal terms in rare disease: Phase 2 commands a 215% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Preclinical Median Upfront: $36MPhase 2 Median Upfront: $285M
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Phase 1 vs Phase 2 — Hematology Deal Valuation Comparison

Compare Phase 1 vs Phase 2 deal terms in hematology: Phase 2 commands a 85% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 1 Median Upfront: $200MPhase 2 Median Upfront: $604M
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Phase 2 vs Phase 3 — Hematology Deal Valuation Comparison

Compare Phase 2 vs Phase 3 deal terms in hematology: Phase 3 commands a 129% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 2 Median Upfront: $604MPhase 3 Median Upfront: $2.0B
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Phase 1 vs Phase 2 — Dermatology Deal Valuation Comparison

Compare Phase 1 vs Phase 2 deal terms in dermatology: Phase 2 commands a 129% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 1 Median Upfront: $104MPhase 2 Median Upfront: $393M
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Phase 2 vs Phase 3 — Dermatology Deal Valuation Comparison

Compare Phase 2 vs Phase 3 deal terms in dermatology: Phase 3 commands a 119% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 2 Median Upfront: $393MPhase 3 Median Upfront: $1.3B
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Phase 1 vs Phase 2 — Gastroenterology Deal Valuation Comparison

Compare Phase 1 vs Phase 2 deal terms in gastroenterology: Phase 2 commands a 122% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 1 Median Upfront: $147MPhase 2 Median Upfront: $529M
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Phase 2 vs Phase 3 — Gastroenterology Deal Valuation Comparison

Compare Phase 2 vs Phase 3 deal terms in gastroenterology: Phase 3 commands a 110% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 2 Median Upfront: $529MPhase 3 Median Upfront: $1.7B
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Phase 1 vs Phase 2 — Cardiovascular Deal Valuation Comparison

Compare Phase 1 vs Phase 2 deal terms in cardiovascular: Phase 2 commands a 125% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 1 Median Upfront: $157MPhase 2 Median Upfront: $606M
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Phase 2 vs Phase 3 — Cardiovascular Deal Valuation Comparison

Compare Phase 2 vs Phase 3 deal terms in cardiovascular: Phase 3 commands a 78% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 2 Median Upfront: $606MPhase 3 Median Upfront: $1.7B
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Phase 1 vs Phase 2 — Infectious Disease Deal Valuation Comparison

Compare Phase 1 vs Phase 2 deal terms in infectious disease: Phase 2 commands a 100% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 1 Median Upfront: $194MPhase 2 Median Upfront: $604M
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Phase 2 vs Phase 3 — Infectious Disease Deal Valuation Comparison

Compare Phase 2 vs Phase 3 deal terms in infectious disease: Phase 3 commands a 79% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 2 Median Upfront: $604MPhase 3 Median Upfront: $1.5B
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Phase 1 vs Phase 2 — Ophthalmology Deal Valuation Comparison

Compare Phase 1 vs Phase 2 deal terms in ophthalmology: Phase 2 commands a 113% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 1 Median Upfront: $244MPhase 2 Median Upfront: $768M
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Phase 2 vs Phase 3 — Ophthalmology Deal Valuation Comparison

Compare Phase 2 vs Phase 3 deal terms in ophthalmology: Phase 3 commands a 87% premium. Side-by-side upfronts, milestones, and royalty benchmarks.

Phase 2 Median Upfront: $768MPhase 3 Median Upfront: $2.1B
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Oncology vs Neurology — Deal Terms Comparison

Compare oncology vs neurology licensing deal terms: Oncology median upfront $258M vs Neurology $343M. Side-by-side TA benchmarks from 2,500+ deals.

Oncology Median Upfront: $258MNeurology Median Upfront: $343M
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Oncology vs Immunology — Deal Terms Comparison

Compare oncology vs immunology licensing deal terms: Oncology median upfront $258M vs Immunology $480M. Side-by-side TA benchmarks from 2,500+ deals.

Oncology Median Upfront: $258MImmunology Median Upfront: $480M
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Oncology vs Metabolic — Deal Terms Comparison

Compare oncology vs metabolic licensing deal terms: Oncology median upfront $258M vs Metabolic $935M. Side-by-side TA benchmarks from 2,500+ deals.

Oncology Median Upfront: $258MMetabolic Median Upfront: $935M
View benchmarks

Oncology vs Hematology — Deal Terms Comparison

Compare oncology vs hematology licensing deal terms: Oncology median upfront $258M vs Hematology $604M. Side-by-side TA benchmarks from 2,500+ deals.

Oncology Median Upfront: $258MHematology Median Upfront: $604M
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Oncology vs Rare Disease — Deal Terms Comparison

Compare oncology vs rare disease licensing deal terms: Oncology median upfront $258M vs Rare Disease $285M. Side-by-side TA benchmarks from 2,500+ deals.

Oncology Median Upfront: $258MRare Disease Median Upfront: $285M
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Oncology vs Cardiovascular — Deal Terms Comparison

Compare oncology vs cardiovascular licensing deal terms: Oncology median upfront $258M vs Cardiovascular $606M. Side-by-side TA benchmarks from 2,500+ deals.

Oncology Median Upfront: $258MCardiovascular Median Upfront: $606M
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Neurology vs Immunology — Deal Terms Comparison

Compare neurology vs immunology licensing deal terms: Neurology median upfront $343M vs Immunology $480M. Side-by-side TA benchmarks from 2,500+ deals.

Neurology Median Upfront: $343MImmunology Median Upfront: $480M
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Neurology vs Metabolic — Deal Terms Comparison

Compare neurology vs metabolic licensing deal terms: Neurology median upfront $343M vs Metabolic $935M. Side-by-side TA benchmarks from 2,500+ deals.

Neurology Median Upfront: $343MMetabolic Median Upfront: $935M
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Neurology vs Rare Disease — Deal Terms Comparison

Compare neurology vs rare disease licensing deal terms: Neurology median upfront $343M vs Rare Disease $285M. Side-by-side TA benchmarks from 2,500+ deals.

Neurology Median Upfront: $343MRare Disease Median Upfront: $285M
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Neurology vs Dermatology — Deal Terms Comparison

Compare neurology vs dermatology licensing deal terms: Neurology median upfront $343M vs Dermatology $393M. Side-by-side TA benchmarks from 2,500+ deals.

Neurology Median Upfront: $343MDermatology Median Upfront: $393M
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Immunology vs Dermatology — Deal Terms Comparison

Compare immunology vs dermatology licensing deal terms: Immunology median upfront $480M vs Dermatology $393M. Side-by-side TA benchmarks from 2,500+ deals.

Immunology Median Upfront: $480MDermatology Median Upfront: $393M
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Immunology vs Gastroenterology — Deal Terms Comparison

Compare immunology vs gastroenterology licensing deal terms: Immunology median upfront $480M vs Gastroenterology $529M. Side-by-side TA benchmarks from 2,500+ deals.

Immunology Median Upfront: $480MGastroenterology Median Upfront: $529M
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Immunology vs Metabolic — Deal Terms Comparison

Compare immunology vs metabolic licensing deal terms: Immunology median upfront $480M vs Metabolic $935M. Side-by-side TA benchmarks from 2,500+ deals.

Immunology Median Upfront: $480MMetabolic Median Upfront: $935M
View benchmarks

Immunology vs Rare Disease — Deal Terms Comparison

Compare immunology vs rare disease licensing deal terms: Immunology median upfront $480M vs Rare Disease $285M. Side-by-side TA benchmarks from 2,500+ deals.

Immunology Median Upfront: $480MRare Disease Median Upfront: $285M
View benchmarks

Metabolic vs Cardiovascular — Deal Terms Comparison

Compare metabolic vs cardiovascular licensing deal terms: Metabolic median upfront $935M vs Cardiovascular $606M. Side-by-side TA benchmarks from 2,500+ deals.

Metabolic Median Upfront: $935MCardiovascular Median Upfront: $606M
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Metabolic vs Rare Disease — Deal Terms Comparison

Compare metabolic vs rare disease licensing deal terms: Metabolic median upfront $935M vs Rare Disease $285M. Side-by-side TA benchmarks from 2,500+ deals.

Metabolic Median Upfront: $935MRare Disease Median Upfront: $285M
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Rare Disease vs Hematology — Deal Terms Comparison

Compare rare disease vs hematology licensing deal terms: Rare Disease median upfront $285M vs Hematology $604M. Side-by-side TA benchmarks from 2,500+ deals.

Rare Disease Median Upfront: $285MHematology Median Upfront: $604M
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Rare Disease vs Ophthalmology — Deal Terms Comparison

Compare rare disease vs ophthalmology licensing deal terms: Rare Disease median upfront $285M vs Ophthalmology $768M. Side-by-side TA benchmarks from 2,500+ deals.

Rare Disease Median Upfront: $285MOphthalmology Median Upfront: $768M
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Hematology vs Immunology — Deal Terms Comparison

Compare hematology vs immunology licensing deal terms: Hematology median upfront $604M vs Immunology $480M. Side-by-side TA benchmarks from 2,500+ deals.

Hematology Median Upfront: $604MImmunology Median Upfront: $480M
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Dermatology vs Gastroenterology — Deal Terms Comparison

Compare dermatology vs gastroenterology licensing deal terms: Dermatology median upfront $393M vs Gastroenterology $529M. Side-by-side TA benchmarks from 2,500+ deals.

Dermatology Median Upfront: $393MGastroenterology Median Upfront: $529M
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Cardiovascular vs Metabolic — Deal Terms Comparison

Compare cardiovascular vs metabolic licensing deal terms: Cardiovascular median upfront $606M vs Metabolic $935M. Side-by-side TA benchmarks from 2,500+ deals.

Cardiovascular Median Upfront: $606MMetabolic Median Upfront: $935M
View benchmarks

Infectious Disease vs Oncology — Deal Terms Comparison

Compare infectious disease vs oncology licensing deal terms: Infectious Disease median upfront $604M vs Oncology $258M. Side-by-side TA benchmarks from 2,500+ deals.

Infectious Disease Median Upfront: $604MOncology Median Upfront: $258M
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Ophthalmology vs Rare Disease — Deal Terms Comparison

Compare ophthalmology vs rare disease licensing deal terms: Ophthalmology median upfront $768M vs Rare Disease $285M. Side-by-side TA benchmarks from 2,500+ deals.

Ophthalmology Median Upfront: $768MRare Disease Median Upfront: $285M
View benchmarks

Hematology vs Oncology — Deal Terms Comparison

Compare hematology vs oncology licensing deal terms: Hematology median upfront $604M vs Oncology $258M. Side-by-side TA benchmarks from 2,500+ deals.

Hematology Median Upfront: $604MOncology Median Upfront: $258M
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Gastroenterology vs Immunology — Deal Terms Comparison

Compare gastroenterology vs immunology licensing deal terms: Gastroenterology median upfront $529M vs Immunology $480M. Side-by-side TA benchmarks from 2,500+ deals.

Gastroenterology Median Upfront: $529MImmunology Median Upfront: $480M
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Dermatology vs Immunology — Deal Terms Comparison

Compare dermatology vs immunology licensing deal terms: Dermatology median upfront $393M vs Immunology $480M. Side-by-side TA benchmarks from 2,500+ deals.

Dermatology Median Upfront: $393MImmunology Median Upfront: $480M
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Neurology vs Cardiovascular — Deal Terms Comparison

Compare neurology vs cardiovascular licensing deal terms: Neurology median upfront $343M vs Cardiovascular $606M. Side-by-side TA benchmarks from 2,500+ deals.

Neurology Median Upfront: $343MCardiovascular Median Upfront: $606M
View benchmarks

Metabolic vs Gastroenterology — Deal Terms Comparison

Compare metabolic vs gastroenterology licensing deal terms: Metabolic median upfront $935M vs Gastroenterology $529M. Side-by-side TA benchmarks from 2,500+ deals.

Metabolic Median Upfront: $935MGastroenterology Median Upfront: $529M
View benchmarks

Oncology vs Infectious Disease — Deal Terms Comparison

Compare oncology vs infectious disease licensing deal terms: Oncology median upfront $258M vs Infectious Disease $604M. Side-by-side TA benchmarks from 2,500+ deals.

Oncology Median Upfront: $258MInfectious Disease Median Upfront: $604M
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Oncology vs Dermatology — Deal Terms Comparison

Compare oncology vs dermatology licensing deal terms: Oncology median upfront $258M vs Dermatology $393M. Side-by-side TA benchmarks from 2,500+ deals.

Oncology Median Upfront: $258MDermatology Median Upfront: $393M
View benchmarks

Oncology vs Gastroenterology — Deal Terms Comparison

Compare oncology vs gastroenterology licensing deal terms: Oncology median upfront $258M vs Gastroenterology $529M. Side-by-side TA benchmarks from 2,500+ deals.

Oncology Median Upfront: $258MGastroenterology Median Upfront: $529M
View benchmarks

Oncology vs Ophthalmology — Deal Terms Comparison

Compare oncology vs ophthalmology licensing deal terms: Oncology median upfront $258M vs Ophthalmology $768M. Side-by-side TA benchmarks from 2,500+ deals.

Oncology Median Upfront: $258MOphthalmology Median Upfront: $768M
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Neurology vs Hematology — Deal Terms Comparison

Compare neurology vs hematology licensing deal terms: Neurology median upfront $343M vs Hematology $604M. Side-by-side TA benchmarks from 2,500+ deals.

Neurology Median Upfront: $343MHematology Median Upfront: $604M
View benchmarks

Immunology vs Ophthalmology — Deal Terms Comparison

Compare immunology vs ophthalmology licensing deal terms: Immunology median upfront $480M vs Ophthalmology $768M. Side-by-side TA benchmarks from 2,500+ deals.

Immunology Median Upfront: $480MOphthalmology Median Upfront: $768M
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Immunology vs Infectious Disease — Deal Terms Comparison

Compare immunology vs infectious disease licensing deal terms: Immunology median upfront $480M vs Infectious Disease $604M. Side-by-side TA benchmarks from 2,500+ deals.

Immunology Median Upfront: $480MInfectious Disease Median Upfront: $604M
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Cardiovascular vs Infectious Disease — Deal Terms Comparison

Compare cardiovascular vs infectious disease licensing deal terms: Cardiovascular median upfront $606M vs Infectious Disease $604M. Side-by-side TA benchmarks from 2,500+ deals.

Cardiovascular Median Upfront: $606MInfectious Disease Median Upfront: $604M
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Metabolic vs Ophthalmology — Deal Terms Comparison

Compare metabolic vs ophthalmology licensing deal terms: Metabolic median upfront $935M vs Ophthalmology $768M. Side-by-side TA benchmarks from 2,500+ deals.

Metabolic Median Upfront: $935MOphthalmology Median Upfront: $768M
View benchmarks

Rare Disease vs Dermatology — Deal Terms Comparison

Compare rare disease vs dermatology licensing deal terms: Rare Disease median upfront $285M vs Dermatology $393M. Side-by-side TA benchmarks from 2,500+ deals.

Rare Disease Median Upfront: $285MDermatology Median Upfront: $393M
View benchmarks

Hematology vs Dermatology — Deal Terms Comparison

Compare hematology vs dermatology licensing deal terms: Hematology median upfront $604M vs Dermatology $393M. Side-by-side TA benchmarks from 2,500+ deals.

Hematology Median Upfront: $604MDermatology Median Upfront: $393M
View benchmarks

Gastroenterology vs Metabolic — Deal Terms Comparison

Compare gastroenterology vs metabolic licensing deal terms: Gastroenterology median upfront $529M vs Metabolic $935M. Side-by-side TA benchmarks from 2,500+ deals.

Gastroenterology Median Upfront: $529MMetabolic Median Upfront: $935M
View benchmarks

Cardiovascular vs Hematology — Deal Terms Comparison

Compare cardiovascular vs hematology licensing deal terms: Cardiovascular median upfront $606M vs Hematology $604M. Side-by-side TA benchmarks from 2,500+ deals.

Cardiovascular Median Upfront: $606MHematology Median Upfront: $604M
View benchmarks

Immunology vs Cardiovascular — Deal Terms Comparison

Compare immunology vs cardiovascular licensing deal terms: Immunology median upfront $480M vs Cardiovascular $606M. Side-by-side TA benchmarks from 2,500+ deals.

Immunology Median Upfront: $480MCardiovascular Median Upfront: $606M
View benchmarks

Rare Disease vs Cardiovascular — Deal Terms Comparison

Compare rare disease vs cardiovascular licensing deal terms: Rare Disease median upfront $285M vs Cardiovascular $606M. Side-by-side TA benchmarks from 2,500+ deals.

Rare Disease Median Upfront: $285MCardiovascular Median Upfront: $606M
View benchmarks

Infectious Disease vs Neurology — Deal Terms Comparison

Compare infectious disease vs neurology licensing deal terms: Infectious Disease median upfront $604M vs Neurology $343M. Side-by-side TA benchmarks from 2,500+ deals.

Infectious Disease Median Upfront: $604MNeurology Median Upfront: $343M
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Rare Disease vs Gastroenterology — Deal Terms Comparison

Compare rare disease vs gastroenterology licensing deal terms: Rare Disease median upfront $285M vs Gastroenterology $529M. Side-by-side TA benchmarks from 2,500+ deals.

Rare Disease Median Upfront: $285MGastroenterology Median Upfront: $529M
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Ophthalmology vs Neurology — Deal Terms Comparison

Compare ophthalmology vs neurology licensing deal terms: Ophthalmology median upfront $768M vs Neurology $343M. Side-by-side TA benchmarks from 2,500+ deals.

Ophthalmology Median Upfront: $768MNeurology Median Upfront: $343M
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Dermatology vs Cardiovascular — Deal Terms Comparison

Compare dermatology vs cardiovascular licensing deal terms: Dermatology median upfront $393M vs Cardiovascular $606M. Side-by-side TA benchmarks from 2,500+ deals.

Dermatology Median Upfront: $393MCardiovascular Median Upfront: $606M
View benchmarks

Infectious Disease vs Metabolic — Deal Terms Comparison

Compare infectious disease vs metabolic licensing deal terms: Infectious Disease median upfront $604M vs Metabolic $935M. Side-by-side TA benchmarks from 2,500+ deals.

Infectious Disease Median Upfront: $604MMetabolic Median Upfront: $935M
View benchmarks

Hematology vs Gastroenterology — Deal Terms Comparison

Compare hematology vs gastroenterology licensing deal terms: Hematology median upfront $604M vs Gastroenterology $529M. Side-by-side TA benchmarks from 2,500+ deals.

Hematology Median Upfront: $604MGastroenterology Median Upfront: $529M
View benchmarks

Ophthalmology vs Dermatology — Deal Terms Comparison

Compare ophthalmology vs dermatology licensing deal terms: Ophthalmology median upfront $768M vs Dermatology $393M. Side-by-side TA benchmarks from 2,500+ deals.

Ophthalmology Median Upfront: $768MDermatology Median Upfront: $393M
View benchmarks

By Modality

Deal benchmarks segmented by drug modality — ADCs, CAR-T, bispecifics, gene therapy, and more.

ADC Licensing Deal Benchmarks

ADC licensing deals average $2.5B total value with $393M upfront at Phase 2. Explore benchmark deal terms for antibody-drug conjugates.

Median Upfront: $393MTotal Deal Value: $2.5B
View benchmarks

CAR-T Cell Therapy Deal Benchmarks

CAR-T licensing deals average $1.0B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for hematologic CAR-T cell therapies.

Median Upfront: $104MTotal Deal Value: $1.0B
View benchmarks

Bispecific Antibody Deal Benchmarks

Bispecific antibody licensing deals average $2.2B total value at Phase 2. Benchmark upfronts, milestones, and royalties for bispecific deals.

Median Upfront: $348MTotal Deal Value: $2.2B
View benchmarks

Radiopharmaceutical Deal Benchmarks

Radiopharmaceutical deals average $1.5B total value at Phase 1. Explore upfront payments, milestones, and royalty benchmarks for RPT licensing.

Median Upfront: $148MTotal Deal Value: $1.5B
View benchmarks

Gene Therapy & Gene Editing Deal Benchmarks

Gene therapy licensing deals average $864M total value at Phase 1. Benchmark upfronts, milestones, and royalty rates for gene therapy and gene editing deals.

Median Upfront: $88MTotal Deal Value: $864M
View benchmarks

Small Molecule Licensing Deal Benchmarks

Small molecule licensing deals average $1.6B total value at Phase 2. Comprehensive benchmarks for upfronts, milestones, and royalties.

Median Upfront: $258MTotal Deal Value: $1.6B
View benchmarks

GLP-1 Agonist Obesity Deal Benchmarks 2026

GLP-1 agonist obesity deals average $4.5B total value at Phase 2. Compare injectable vs oral GLP-1 deal terms, upfronts, milestones, and royalties.

Median Upfront: $935MTotal Deal Value: $4.5B
View benchmarks

Dual & Triple Incretin Deal Benchmarks 2026

Dual incretin (GLP-1/GIP) deals average $5.5B total value. Compare dual vs triple agonist deal terms and benchmarks.

Median Upfront: $1.1BTotal Deal Value: $5.5B
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Oral Peptide & Oral GLP-1 Deal Benchmarks 2026

Oral peptide obesity deals average $5.1B total value — 20-30% premium over injectables. Benchmark oral GLP-1 deal terms.

Median Upfront: $1.1BTotal Deal Value: $5.1B
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Gene Therapy Rare Disease Deal Benchmarks

Gene therapy rare disease deals average $1.2B total value at Phase 1. Benchmark upfronts, milestones, and royalties for orphan gene therapy licensing.

Median Upfront: $126MTotal Deal Value: $1.2B
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Enzyme Replacement Therapy Deal Benchmarks

ERT licensing deals average $2.3B total value at Phase 2. Benchmark deal terms for enzyme replacement therapies targeting Fabry, Gaucher, and Pompe disease.

Median Upfront: $425MTotal Deal Value: $2.3B
View benchmarks

CAR-T Hematology Deal Benchmarks

CAR-T hematology deals average $2.1B total value at Phase 1. Benchmark upfronts, milestones, and royalties for hematologic CAR-T cell therapy licensing.

Median Upfront: $247MTotal Deal Value: $2.1B
View benchmarks

Bispecific Antibody Hematology Deal Benchmarks

Bispecific antibody hematology deals average $3.6B total value at Phase 2. Benchmark deal terms for hematologic bispecific antibody licensing.

Median Upfront: $717MTotal Deal Value: $3.6B
View benchmarks

IL-17 Inhibitor Deal Benchmarks

IL-17 inhibitor licensing deals average $2.1B total value at Phase 2. Benchmark upfronts, milestones, and royalties for IL-17 pathway deals.

Median Upfront: $400MTotal Deal Value: $2.1B
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JAK Inhibitor Dermatology Deal Benchmarks

JAK inhibitor dermatology deals average $2.0B total value at Phase 2. Benchmark deal terms for JAK inhibitors in atopic dermatitis, alopecia areata, and vitiligo.

Median Upfront: $370MTotal Deal Value: $2.0B
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Anti-TL1A Deal Benchmarks

Anti-TL1A licensing deals average $3.3B total value at Phase 2. Benchmark deal terms for TL1A-targeting therapies in Crohn's disease and ulcerative colitis.

Median Upfront: $620MTotal Deal Value: $3.3B
View benchmarks

IL-23 GI Deal Benchmarks

IL-23 inhibitor GI deals average $3.0B total value at Phase 2. Benchmark deal terms for IL-23 targeting therapies in ulcerative colitis and Crohn's disease.

Median Upfront: $568MTotal Deal Value: $3.0B
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Checkpoint Inhibitor (PD-1/PD-L1) Deal Benchmarks

Checkpoint inhibitor licensing deals average $1.7B total value at Phase 2. Benchmark PD-1/PD-L1 IO deal terms, milestones, and royalties.

Median Upfront: $266MTotal Deal Value: $1.7B
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RNAi & siRNA Licensing Deal Benchmarks

RNAi/siRNA licensing deals average $1.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for RNA interference therapeutics.

Median Upfront: $253MTotal Deal Value: $1.6B
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PROTAC & Targeted Protein Degrader Deal Benchmarks

PROTAC/degrader licensing deals average $1.0B total value at Phase 1. Benchmark upfronts, milestones, and royalties for targeted protein degradation deals.

Median Upfront: $104MTotal Deal Value: $1.0B
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mRNA Therapeutics Deal Benchmarks

mRNA therapeutics licensing deals average $2.5B total value at Phase 2. Benchmark upfronts, milestones, and royalties for mRNA platform deals.

Median Upfront: $649MTotal Deal Value: $2.5B
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Monoclonal Antibody (mAb) Licensing Deal Benchmarks

Monoclonal antibody licensing deals average $2.5B total value at Phase 2. Benchmark upfronts, milestones, and royalties for mAb deals.

Median Upfront: $476MTotal Deal Value: $2.5B
View benchmarks

Cell Therapy Deal Benchmarks (Beyond CAR-T)

Non-CAR-T cell therapy deals average $1.0B total value at Phase 1. Benchmark upfronts, milestones, and royalties for TIL, NK cell, and iPSC-derived therapies.

Median Upfront: $103MTotal Deal Value: $1.0B
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Precision Oncology & Biomarker-Driven Deal Benchmarks

Biomarker-selected oncology deals average $1.9B total value at Phase 2. Benchmark upfronts, milestones, and royalties for precision medicine deals.

Median Upfront: $292MTotal Deal Value: $1.9B
View benchmarks

Obesity & Weight Loss Drug Deal Benchmarks 2026

Obesity/weight loss drug deals average $7.5B total value at Phase 3. Benchmark upfronts, milestones, and royalties for GLP-1 agonist licensing.

Median Upfront: $2.0BTotal Deal Value: $7.5B
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Autoimmune Biologics Deal Benchmarks

Autoimmune biologics licensing deals average $3.0B total value at Phase 2. Benchmark upfronts, milestones, and royalties for autoimmune biologic deals.

Median Upfront: $575MTotal Deal Value: $3.0B
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Rare Disease Gene Therapy Deal Benchmarks 2026

Rare disease gene therapy deals average $1.2B total value at Phase 1 in 2026. Updated benchmarks for orphan gene therapy upfronts, milestones, and royalties.

Median Upfront: $123MTotal Deal Value: $1.2B
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Approved Drug Licensing & Out-Licensing Deal Benchmarks

Approved drug licensing deals average $5.7B total value. Benchmark upfronts, milestones, and royalties for marketed product out-licensing deals.

Median Upfront: $2.1BTotal Deal Value: $5.7B
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Small Molecule Deal Benchmarks in Oncology

Comprehensive small molecule licensing and acquisition deal benchmarks for oncology. Median upfront $258M, total deal value $1.6B, and royalty rates from 2,500+ verified deals.

Median Upfront: $258MTotal Deal Value: $1.6B
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Monoclonal Antibody Deal Benchmarks in Oncology

Comprehensive monoclonal antibody licensing and acquisition deal benchmarks for oncology. Median upfront $266M, total deal value $1.7B, and royalty rates from 2,500+ verified deals.

Median Upfront: $266MTotal Deal Value: $1.7B
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ADC (Antibody-Drug Conjugate) Deal Benchmarks in Oncology

Comprehensive adc (antibody-drug conjugate) licensing and acquisition deal benchmarks for oncology. Median upfront $411M, total deal value $2.6B, and royalty rates from 2,500+ verified deals.

Median Upfront: $411MTotal Deal Value: $2.6B
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Bispecific Antibody Deal Benchmarks in Oncology

Comprehensive bispecific antibody licensing and acquisition deal benchmarks for oncology. Median upfront $348M, total deal value $2.2B, and royalty rates from 2,500+ verified deals.

Median Upfront: $348MTotal Deal Value: $2.2B
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CAR-T (Hematologic) Deal Benchmarks in Oncology

Comprehensive car-t (hematologic) licensing and acquisition deal benchmarks for oncology. Median upfront $309M, total deal value $2.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $309MTotal Deal Value: $2.0B
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CAR-T (Solid Tumor) Deal Benchmarks in Oncology

Comprehensive car-t (solid tumor) licensing and acquisition deal benchmarks for oncology. Median upfront $356M, total deal value $2.3B, and royalty rates from 2,500+ verified deals.

Median Upfront: $356MTotal Deal Value: $2.3B
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Gene Therapy Deal Benchmarks in Oncology

Comprehensive gene therapy licensing and acquisition deal benchmarks for oncology. Median upfront $253M, total deal value $1.6B, and royalty rates from 2,500+ verified deals.

Median Upfront: $253MTotal Deal Value: $1.6B
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Radiopharmaceutical Deal Benchmarks in Oncology

Comprehensive radiopharmaceutical licensing and acquisition deal benchmarks for oncology. Median upfront $407M, total deal value $2.6B, and royalty rates from 2,500+ verified deals.

Median Upfront: $407MTotal Deal Value: $2.6B
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PROTAC Degrader Deal Benchmarks in Oncology

Comprehensive protac degrader licensing and acquisition deal benchmarks for oncology. Median upfront $348M, total deal value $2.2B, and royalty rates from 2,500+ verified deals.

Median Upfront: $348MTotal Deal Value: $2.2B
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Molecular Glue Deal Benchmarks in Oncology

Comprehensive molecular glue licensing and acquisition deal benchmarks for oncology. Median upfront $361M, total deal value $2.3B, and royalty rates from 2,500+ verified deals.

Median Upfront: $361MTotal Deal Value: $2.3B
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Therapeutic Vaccine Deal Benchmarks in Oncology

Comprehensive therapeutic vaccine licensing and acquisition deal benchmarks for oncology. Median upfront $297M, total deal value $1.9B, and royalty rates from 2,500+ verified deals.

Median Upfront: $297MTotal Deal Value: $1.9B
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Oncolytic Virus Deal Benchmarks in Oncology

Comprehensive oncolytic virus licensing and acquisition deal benchmarks for oncology. Median upfront $280M, total deal value $1.8B, and royalty rates from 2,500+ verified deals.

Median Upfront: $280MTotal Deal Value: $1.8B
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T-Cell Engager Deal Benchmarks in Oncology

Comprehensive t-cell engager licensing and acquisition deal benchmarks for oncology. Median upfront $335M, total deal value $2.1B, and royalty rates from 2,500+ verified deals.

Median Upfront: $335MTotal Deal Value: $2.1B
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Peptide Therapeutic Deal Benchmarks in Oncology

Comprehensive peptide therapeutic licensing and acquisition deal benchmarks for oncology. Median upfront $271M, total deal value $1.7B, and royalty rates from 2,500+ verified deals.

Median Upfront: $271MTotal Deal Value: $1.7B
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RNAi / siRNA Deal Benchmarks in Oncology

Comprehensive rnai / sirna licensing and acquisition deal benchmarks for oncology. Median upfront $297M, total deal value $1.9B, and royalty rates from 2,500+ verified deals.

Median Upfront: $297MTotal Deal Value: $1.9B
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Small Molecule Deal Benchmarks in Neurology

Comprehensive small molecule licensing and acquisition deal benchmarks for neurology. Median upfront $343M, total deal value $3.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $343MTotal Deal Value: $3.0B
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Monoclonal Antibody Deal Benchmarks in Neurology

Comprehensive monoclonal antibody licensing and acquisition deal benchmarks for neurology. Median upfront $354M, total deal value $3.1B, and royalty rates from 2,500+ verified deals.

Median Upfront: $354MTotal Deal Value: $3.1B
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Gene Therapy Deal Benchmarks in Neurology

Comprehensive gene therapy licensing and acquisition deal benchmarks for neurology. Median upfront $331M, total deal value $3.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $331MTotal Deal Value: $3.0B
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Antisense Oligonucleotide (ASO) Deal Benchmarks in Neurology

Comprehensive antisense oligonucleotide (aso) licensing and acquisition deal benchmarks for neurology. Median upfront $389M, total deal value $3.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $389MTotal Deal Value: $3.5B
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BBB Platform Deal Benchmarks in Neurology

Comprehensive bbb platform licensing and acquisition deal benchmarks for neurology. Median upfront $558M, total deal value $5.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $558MTotal Deal Value: $5.0B
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Psychedelic-Derived Deal Benchmarks in Neurology

Comprehensive psychedelic-derived licensing and acquisition deal benchmarks for neurology. Median upfront $378M, total deal value $3.3B, and royalty rates from 2,500+ verified deals.

Median Upfront: $378MTotal Deal Value: $3.3B
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Ion Channel Modulator Deal Benchmarks in Neurology

Comprehensive ion channel modulator licensing and acquisition deal benchmarks for neurology. Median upfront $378M, total deal value $3.3B, and royalty rates from 2,500+ verified deals.

Median Upfront: $378MTotal Deal Value: $3.3B
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Tau-Targeting Deal Benchmarks in Neurology

Comprehensive tau-targeting licensing and acquisition deal benchmarks for neurology. Median upfront $464M, total deal value $4.1B, and royalty rates from 2,500+ verified deals.

Median Upfront: $464MTotal Deal Value: $4.1B
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Stem Cell Therapy Deal Benchmarks in Neurology

Comprehensive stem cell therapy licensing and acquisition deal benchmarks for neurology. Median upfront $395M, total deal value $3.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $395MTotal Deal Value: $3.5B
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Peptide Therapeutic Deal Benchmarks in Neurology

Comprehensive peptide therapeutic licensing and acquisition deal benchmarks for neurology. Median upfront $361M, total deal value $3.2B, and royalty rates from 2,500+ verified deals.

Median Upfront: $361MTotal Deal Value: $3.2B
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RNAi / siRNA Deal Benchmarks in Neurology

Comprehensive rnai / sirna licensing and acquisition deal benchmarks for neurology. Median upfront $395M, total deal value $3.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $395MTotal Deal Value: $3.5B
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Small Molecule Deal Benchmarks in Immunology & Autoimmune

Comprehensive small molecule licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $466M, total deal value $2.4B, and royalty rates from 2,500+ verified deals.

Median Upfront: $466MTotal Deal Value: $2.4B
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Monoclonal Antibody Deal Benchmarks in Immunology & Autoimmune

Comprehensive monoclonal antibody licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $480M, total deal value $2.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $480MTotal Deal Value: $2.5B
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Bispecific Antibody Deal Benchmarks in Immunology & Autoimmune

Comprehensive bispecific antibody licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $629M, total deal value $3.3B, and royalty rates from 2,500+ verified deals.

Median Upfront: $629MTotal Deal Value: $3.3B
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CAR-T (Autoimmune) Deal Benchmarks in Immunology & Autoimmune

Comprehensive car-t (autoimmune) licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $914M, total deal value $5.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $914MTotal Deal Value: $5.0B
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In Vivo CAR-T Deal Benchmarks in Immunology & Autoimmune

Comprehensive in vivo car-t licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $652M, total deal value $3.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $652MTotal Deal Value: $3.5B
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CAR-Treg Deal Benchmarks in Immunology & Autoimmune

Comprehensive car-treg licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $767M, total deal value $4.2B, and royalty rates from 2,500+ verified deals.

Median Upfront: $767MTotal Deal Value: $4.2B
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FcRn Antagonist Deal Benchmarks in Immunology & Autoimmune

Comprehensive fcrn antagonist licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $583M, total deal value $3.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $583MTotal Deal Value: $3.0B
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Complement Inhibitor Deal Benchmarks in Immunology & Autoimmune

Comprehensive complement inhibitor licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $560M, total deal value $2.9B, and royalty rates from 2,500+ verified deals.

Median Upfront: $560MTotal Deal Value: $2.9B
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JAK Inhibitor Deal Benchmarks in Immunology & Autoimmune

Comprehensive jak inhibitor licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $513M, total deal value $2.7B, and royalty rates from 2,500+ verified deals.

Median Upfront: $513MTotal Deal Value: $2.7B
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S1P Modulator Deal Benchmarks in Immunology & Autoimmune

Comprehensive s1p modulator licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $536M, total deal value $2.8B, and royalty rates from 2,500+ verified deals.

Median Upfront: $536MTotal Deal Value: $2.8B
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Oral Integrin Deal Benchmarks in Immunology & Autoimmune

Comprehensive oral integrin licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $629M, total deal value $3.3B, and royalty rates from 2,500+ verified deals.

Median Upfront: $629MTotal Deal Value: $3.3B
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Dual Antagonist Deal Benchmarks in Immunology & Autoimmune

Comprehensive dual antagonist licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $606M, total deal value $3.2B, and royalty rates from 2,500+ verified deals.

Median Upfront: $606MTotal Deal Value: $3.2B
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TL1A Inhibitor Deal Benchmarks in Immunology & Autoimmune

Comprehensive tl1a inhibitor licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $676M, total deal value $3.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $676MTotal Deal Value: $3.5B
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Peptide Therapeutic Deal Benchmarks in Immunology & Autoimmune

Comprehensive peptide therapeutic licensing and acquisition deal benchmarks for immunology & autoimmune. Median upfront $490M, total deal value $2.6B, and royalty rates from 2,500+ verified deals.

Median Upfront: $490MTotal Deal Value: $2.6B
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Small Molecule Deal Benchmarks in Metabolic & Obesity

Comprehensive small molecule licensing and acquisition deal benchmarks for metabolic & obesity. Median upfront $683M, total deal value $3.2B, and royalty rates from 2,500+ verified deals.

Median Upfront: $683MTotal Deal Value: $3.2B
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GLP-1 Agonist Deal Benchmarks in Metabolic & Obesity

Comprehensive glp-1 agonist licensing and acquisition deal benchmarks for metabolic & obesity. Median upfront $935M, total deal value $4.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $935MTotal Deal Value: $4.5B
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Dual Incretin Deal Benchmarks in Metabolic & Obesity

Comprehensive dual incretin licensing and acquisition deal benchmarks for metabolic & obesity. Median upfront $1.2B, total deal value $5.9B, and royalty rates from 2,500+ verified deals.

Median Upfront: $1.2BTotal Deal Value: $5.9B
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Triple Incretin Deal Benchmarks in Metabolic & Obesity

Comprehensive triple incretin licensing and acquisition deal benchmarks for metabolic & obesity. Median upfront $1.2B, total deal value $5.6B, and royalty rates from 2,500+ verified deals.

Median Upfront: $1.2BTotal Deal Value: $5.6B
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SGLT2 Inhibitor Deal Benchmarks in Metabolic & Obesity

Comprehensive sglt2 inhibitor licensing and acquisition deal benchmarks for metabolic & obesity. Median upfront $751M, total deal value $3.6B, and royalty rates from 2,500+ verified deals.

Median Upfront: $751MTotal Deal Value: $3.6B
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Amylin Analog Deal Benchmarks in Metabolic & Obesity

Comprehensive amylin analog licensing and acquisition deal benchmarks for metabolic & obesity. Median upfront $996M, total deal value $4.7B, and royalty rates from 2,500+ verified deals.

Median Upfront: $996MTotal Deal Value: $4.7B
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Oral Peptide Deal Benchmarks in Metabolic & Obesity

Comprehensive oral peptide licensing and acquisition deal benchmarks for metabolic & obesity. Median upfront $1.4B, total deal value $6.7B, and royalty rates from 2,500+ verified deals.

Median Upfront: $1.4BTotal Deal Value: $6.7B
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Anti-Activin Deal Benchmarks in Metabolic & Obesity

Comprehensive anti-activin licensing and acquisition deal benchmarks for metabolic & obesity. Median upfront $1.0B, total deal value $4.9B, and royalty rates from 2,500+ verified deals.

Median Upfront: $1.0BTotal Deal Value: $4.9B
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Microbiome-Based Deal Benchmarks in Metabolic & Obesity

Comprehensive microbiome-based licensing and acquisition deal benchmarks for metabolic & obesity. Median upfront $533M, total deal value $2.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $533MTotal Deal Value: $2.5B
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Peptide Therapeutic Deal Benchmarks in Metabolic & Obesity

Comprehensive peptide therapeutic licensing and acquisition deal benchmarks for metabolic & obesity. Median upfront $717M, total deal value $3.4B, and royalty rates from 2,500+ verified deals.

Median Upfront: $717MTotal Deal Value: $3.4B
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Monoclonal Antibody Deal Benchmarks in Metabolic & Obesity

Comprehensive monoclonal antibody licensing and acquisition deal benchmarks for metabolic & obesity. Median upfront $703M, total deal value $3.3B, and royalty rates from 2,500+ verified deals.

Median Upfront: $703MTotal Deal Value: $3.3B
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Gene Therapy Deal Benchmarks in Metabolic & Obesity

Comprehensive gene therapy licensing and acquisition deal benchmarks for metabolic & obesity. Median upfront $669M, total deal value $3.2B, and royalty rates from 2,500+ verified deals.

Median Upfront: $669MTotal Deal Value: $3.2B
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Small Molecule Deal Benchmarks in Cardiovascular

Comprehensive small molecule licensing and acquisition deal benchmarks for cardiovascular. Median upfront $606M, total deal value $3.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $606MTotal Deal Value: $3.0B
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Monoclonal Antibody Deal Benchmarks in Cardiovascular

Comprehensive monoclonal antibody licensing and acquisition deal benchmarks for cardiovascular. Median upfront $624M, total deal value $3.1B, and royalty rates from 2,500+ verified deals.

Median Upfront: $624MTotal Deal Value: $3.1B
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Myosin Inhibitor Deal Benchmarks in Cardiovascular

Comprehensive myosin inhibitor licensing and acquisition deal benchmarks for cardiovascular. Median upfront $788M, total deal value $4.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $788MTotal Deal Value: $4.0B
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Novel Anticoagulant Deal Benchmarks in Cardiovascular

Comprehensive novel anticoagulant licensing and acquisition deal benchmarks for cardiovascular. Median upfront $727M, total deal value $3.7B, and royalty rates from 2,500+ verified deals.

Median Upfront: $727MTotal Deal Value: $3.7B
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RNA Cardiovascular Deal Benchmarks in Cardiovascular

Comprehensive rna cardiovascular licensing and acquisition deal benchmarks for cardiovascular. Median upfront $757M, total deal value $3.8B, and royalty rates from 2,500+ verified deals.

Median Upfront: $757MTotal Deal Value: $3.8B
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PCSK9-Targeting Deal Benchmarks in Cardiovascular

Comprehensive pcsk9-targeting licensing and acquisition deal benchmarks for cardiovascular. Median upfront $697M, total deal value $3.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $697MTotal Deal Value: $3.5B
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Peptide Therapeutic Deal Benchmarks in Cardiovascular

Comprehensive peptide therapeutic licensing and acquisition deal benchmarks for cardiovascular. Median upfront $636M, total deal value $3.2B, and royalty rates from 2,500+ verified deals.

Median Upfront: $636MTotal Deal Value: $3.2B
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Gene Therapy Deal Benchmarks in Cardiovascular

Comprehensive gene therapy licensing and acquisition deal benchmarks for cardiovascular. Median upfront $594M, total deal value $3.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $594MTotal Deal Value: $3.0B
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RNAi / siRNA Deal Benchmarks in Cardiovascular

Comprehensive rnai / sirna licensing and acquisition deal benchmarks for cardiovascular. Median upfront $697M, total deal value $3.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $697MTotal Deal Value: $3.5B
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Small Molecule Deal Benchmarks in Infectious Disease

Comprehensive small molecule licensing and acquisition deal benchmarks for infectious disease. Median upfront $604M, total deal value $2.3B, and royalty rates from 2,500+ verified deals.

Median Upfront: $604MTotal Deal Value: $2.3B
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Monoclonal Antibody Deal Benchmarks in Infectious Disease

Comprehensive monoclonal antibody licensing and acquisition deal benchmarks for infectious disease. Median upfront $622M, total deal value $2.4B, and royalty rates from 2,500+ verified deals.

Median Upfront: $622MTotal Deal Value: $2.4B
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Antiviral Deal Benchmarks in Infectious Disease

Comprehensive antiviral licensing and acquisition deal benchmarks for infectious disease. Median upfront $664M, total deal value $2.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $664MTotal Deal Value: $2.5B
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Novel Antibiotic Deal Benchmarks in Infectious Disease

Comprehensive novel antibiotic licensing and acquisition deal benchmarks for infectious disease. Median upfront $695M, total deal value $2.7B, and royalty rates from 2,500+ verified deals.

Median Upfront: $695MTotal Deal Value: $2.7B
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Preventive Vaccine Deal Benchmarks in Infectious Disease

Comprehensive preventive vaccine licensing and acquisition deal benchmarks for infectious disease. Median upfront $725M, total deal value $2.8B, and royalty rates from 2,500+ verified deals.

Median Upfront: $725MTotal Deal Value: $2.8B
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Phage Therapy Deal Benchmarks in Infectious Disease

Comprehensive phage therapy licensing and acquisition deal benchmarks for infectious disease. Median upfront $513M, total deal value $2.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $513MTotal Deal Value: $2.0B
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mRNA Therapeutic Deal Benchmarks in Infectious Disease

Comprehensive mrna therapeutic licensing and acquisition deal benchmarks for infectious disease. Median upfront $785M, total deal value $3.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $785MTotal Deal Value: $3.0B
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Peptide Therapeutic Deal Benchmarks in Infectious Disease

Comprehensive peptide therapeutic licensing and acquisition deal benchmarks for infectious disease. Median upfront $634M, total deal value $2.4B, and royalty rates from 2,500+ verified deals.

Median Upfront: $634MTotal Deal Value: $2.4B
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Small Molecule Deal Benchmarks in Ophthalmology

Comprehensive small molecule licensing and acquisition deal benchmarks for ophthalmology. Median upfront $607M, total deal value $2.9B, and royalty rates from 2,500+ verified deals.

Median Upfront: $607MTotal Deal Value: $2.9B
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Monoclonal Antibody Deal Benchmarks in Ophthalmology

Comprehensive monoclonal antibody licensing and acquisition deal benchmarks for ophthalmology. Median upfront $625M, total deal value $2.9B, and royalty rates from 2,500+ verified deals.

Median Upfront: $625MTotal Deal Value: $2.9B
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Anti-VEGF Deal Benchmarks in Ophthalmology

Comprehensive anti-vegf licensing and acquisition deal benchmarks for ophthalmology. Median upfront $768M, total deal value $3.6B, and royalty rates from 2,500+ verified deals.

Median Upfront: $768MTotal Deal Value: $3.6B
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Gene Therapy (Ocular) Deal Benchmarks in Ophthalmology

Comprehensive gene therapy (ocular) licensing and acquisition deal benchmarks for ophthalmology. Median upfront $820M, total deal value $3.9B, and royalty rates from 2,500+ verified deals.

Median Upfront: $820MTotal Deal Value: $3.9B
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Intravitreal Deal Benchmarks in Ophthalmology

Comprehensive intravitreal licensing and acquisition deal benchmarks for ophthalmology. Median upfront $717M, total deal value $3.4B, and royalty rates from 2,500+ verified deals.

Median Upfront: $717MTotal Deal Value: $3.4B
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Topical Ophthalmic Deal Benchmarks in Ophthalmology

Comprehensive topical ophthalmic licensing and acquisition deal benchmarks for ophthalmology. Median upfront $491M, total deal value $2.3B, and royalty rates from 2,500+ verified deals.

Median Upfront: $491MTotal Deal Value: $2.3B
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RNAi / siRNA Deal Benchmarks in Ophthalmology

Comprehensive rnai / sirna licensing and acquisition deal benchmarks for ophthalmology. Median upfront $698M, total deal value $3.3B, and royalty rates from 2,500+ verified deals.

Median Upfront: $698MTotal Deal Value: $3.3B
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Gene Therapy Deal Benchmarks in Rare Disease

Comprehensive gene therapy licensing and acquisition deal benchmarks for rare disease. Median upfront $285M, total deal value $1.6B, and royalty rates from 2,500+ verified deals.

Median Upfront: $285MTotal Deal Value: $1.6B
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Small Molecule Deal Benchmarks in Rare Disease

Comprehensive small molecule licensing and acquisition deal benchmarks for rare disease. Median upfront $446M, total deal value $2.4B, and royalty rates from 2,500+ verified deals.

Median Upfront: $446MTotal Deal Value: $2.4B
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Monoclonal Antibody Deal Benchmarks in Rare Disease

Comprehensive monoclonal antibody licensing and acquisition deal benchmarks for rare disease. Median upfront $409M, total deal value $2.2B, and royalty rates from 2,500+ verified deals.

Median Upfront: $409MTotal Deal Value: $2.2B
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Antisense Oligonucleotide (ASO) Deal Benchmarks in Rare Disease

Comprehensive antisense oligonucleotide (aso) licensing and acquisition deal benchmarks for rare disease. Median upfront $456M, total deal value $2.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $456MTotal Deal Value: $2.5B
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RNAi / siRNA Deal Benchmarks in Rare Disease

Comprehensive rnai / sirna licensing and acquisition deal benchmarks for rare disease. Median upfront $456M, total deal value $2.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $456MTotal Deal Value: $2.5B
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Cell Therapy Deal Benchmarks in Rare Disease

Comprehensive cell therapy licensing and acquisition deal benchmarks for rare disease. Median upfront $456M, total deal value $2.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $456MTotal Deal Value: $2.5B
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Peptide Therapeutic Deal Benchmarks in Rare Disease

Comprehensive peptide therapeutic licensing and acquisition deal benchmarks for rare disease. Median upfront $416M, total deal value $2.2B, and royalty rates from 2,500+ verified deals.

Median Upfront: $416MTotal Deal Value: $2.2B
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Oligonucleotide Deal Benchmarks in Rare Disease

Comprehensive oligonucleotide licensing and acquisition deal benchmarks for rare disease. Median upfront $468M, total deal value $2.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $468MTotal Deal Value: $2.5B
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CAR-T (Hematologic) Deal Benchmarks in Hematology

Comprehensive car-t (hematologic) licensing and acquisition deal benchmarks for hematology. Median upfront $751M, total deal value $3.8B, and royalty rates from 2,500+ verified deals.

Median Upfront: $751MTotal Deal Value: $3.8B
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Bispecific Antibody Deal Benchmarks in Hematology

Comprehensive bispecific antibody licensing and acquisition deal benchmarks for hematology. Median upfront $871M, total deal value $4.3B, and royalty rates from 2,500+ verified deals.

Median Upfront: $871MTotal Deal Value: $4.3B
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Small Molecule Deal Benchmarks in Hematology

Comprehensive small molecule licensing and acquisition deal benchmarks for hematology. Median upfront $604M, total deal value $3.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $604MTotal Deal Value: $3.0B
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Monoclonal Antibody Deal Benchmarks in Hematology

Comprehensive monoclonal antibody licensing and acquisition deal benchmarks for hematology. Median upfront $622M, total deal value $3.1B, and royalty rates from 2,500+ verified deals.

Median Upfront: $622MTotal Deal Value: $3.1B
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Gene Therapy Deal Benchmarks in Hematology

Comprehensive gene therapy licensing and acquisition deal benchmarks for hematology. Median upfront $592M, total deal value $2.9B, and royalty rates from 2,500+ verified deals.

Median Upfront: $592MTotal Deal Value: $2.9B
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Cell Therapy Deal Benchmarks in Hematology

Comprehensive cell therapy licensing and acquisition deal benchmarks for hematology. Median upfront $695M, total deal value $3.4B, and royalty rates from 2,500+ verified deals.

Median Upfront: $695MTotal Deal Value: $3.4B
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RNAi / siRNA Deal Benchmarks in Hematology

Comprehensive rnai / sirna licensing and acquisition deal benchmarks for hematology. Median upfront $695M, total deal value $3.4B, and royalty rates from 2,500+ verified deals.

Median Upfront: $695MTotal Deal Value: $3.4B
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Antisense Oligonucleotide (ASO) Deal Benchmarks in Hematology

Comprehensive antisense oligonucleotide (aso) licensing and acquisition deal benchmarks for hematology. Median upfront $695M, total deal value $3.4B, and royalty rates from 2,500+ verified deals.

Median Upfront: $695MTotal Deal Value: $3.4B
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Small Molecule Deal Benchmarks in Dermatology

Comprehensive small molecule licensing and acquisition deal benchmarks for dermatology. Median upfront $393M, total deal value $2.1B, and royalty rates from 2,500+ verified deals.

Median Upfront: $393MTotal Deal Value: $2.1B
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Monoclonal Antibody Deal Benchmarks in Dermatology

Comprehensive monoclonal antibody licensing and acquisition deal benchmarks for dermatology. Median upfront $405M, total deal value $2.2B, and royalty rates from 2,500+ verified deals.

Median Upfront: $405MTotal Deal Value: $2.2B
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JAK Inhibitor Deal Benchmarks in Dermatology

Comprehensive jak inhibitor licensing and acquisition deal benchmarks for dermatology. Median upfront $433M, total deal value $2.3B, and royalty rates from 2,500+ verified deals.

Median Upfront: $433MTotal Deal Value: $2.3B
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Peptide Therapeutic Deal Benchmarks in Dermatology

Comprehensive peptide therapeutic licensing and acquisition deal benchmarks for dermatology. Median upfront $413M, total deal value $2.2B, and royalty rates from 2,500+ verified deals.

Median Upfront: $413MTotal Deal Value: $2.2B
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Topical Ophthalmic Deal Benchmarks in Dermatology

Comprehensive topical ophthalmic licensing and acquisition deal benchmarks for dermatology. Median upfront $383M, total deal value $2.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $383MTotal Deal Value: $2.0B
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Small Molecule Deal Benchmarks in Gastroenterology

Comprehensive small molecule licensing and acquisition deal benchmarks for gastroenterology. Median upfront $514M, total deal value $2.6B, and royalty rates from 2,500+ verified deals.

Median Upfront: $514MTotal Deal Value: $2.6B
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Monoclonal Antibody Deal Benchmarks in Gastroenterology

Comprehensive monoclonal antibody licensing and acquisition deal benchmarks for gastroenterology. Median upfront $529M, total deal value $2.7B, and royalty rates from 2,500+ verified deals.

Median Upfront: $529MTotal Deal Value: $2.7B
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Oral Integrin Deal Benchmarks in Gastroenterology

Comprehensive oral integrin licensing and acquisition deal benchmarks for gastroenterology. Median upfront $693M, total deal value $3.5B, and royalty rates from 2,500+ verified deals.

Median Upfront: $693MTotal Deal Value: $3.5B
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JAK Inhibitor Deal Benchmarks in Gastroenterology

Comprehensive jak inhibitor licensing and acquisition deal benchmarks for gastroenterology. Median upfront $565M, total deal value $2.9B, and royalty rates from 2,500+ verified deals.

Median Upfront: $565MTotal Deal Value: $2.9B
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S1P Modulator Deal Benchmarks in Gastroenterology

Comprehensive s1p modulator licensing and acquisition deal benchmarks for gastroenterology. Median upfront $586M, total deal value $3.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $586MTotal Deal Value: $3.0B
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TL1A Inhibitor Deal Benchmarks in Gastroenterology

Comprehensive tl1a inhibitor licensing and acquisition deal benchmarks for gastroenterology. Median upfront $745M, total deal value $3.8B, and royalty rates from 2,500+ verified deals.

Median Upfront: $745MTotal Deal Value: $3.8B
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Peptide Therapeutic Deal Benchmarks in Gastroenterology

Comprehensive peptide therapeutic licensing and acquisition deal benchmarks for gastroenterology. Median upfront $539M, total deal value $2.7B, and royalty rates from 2,500+ verified deals.

Median Upfront: $539MTotal Deal Value: $2.7B
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Microbiome-Based Deal Benchmarks in Gastroenterology

Comprehensive microbiome-based licensing and acquisition deal benchmarks for gastroenterology. Median upfront $401M, total deal value $2.0B, and royalty rates from 2,500+ verified deals.

Median Upfront: $401MTotal Deal Value: $2.0B
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Small Molecule Deal Benchmarks in Women's Health

Comprehensive small molecule licensing and acquisition deal benchmarks for women's health. Median upfront $326M, total deal value $1.8B, and royalty rates from 2,500+ verified deals.

Median Upfront: $326MTotal Deal Value: $1.8B
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Monoclonal Antibody Deal Benchmarks in Women's Health

Comprehensive monoclonal antibody licensing and acquisition deal benchmarks for women's health. Median upfront $336M, total deal value $1.8B, and royalty rates from 2,500+ verified deals.

Median Upfront: $336MTotal Deal Value: $1.8B
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Peptide Therapeutic Deal Benchmarks in Women's Health

Comprehensive peptide therapeutic licensing and acquisition deal benchmarks for women's health. Median upfront $342M, total deal value $1.9B, and royalty rates from 2,500+ verified deals.

Median Upfront: $342MTotal Deal Value: $1.9B
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Gene Therapy Deal Benchmarks in Women's Health

Comprehensive gene therapy licensing and acquisition deal benchmarks for women's health. Median upfront $319M, total deal value $1.8B, and royalty rates from 2,500+ verified deals.

Median Upfront: $319MTotal Deal Value: $1.8B
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By Indication

Deal benchmarks for specific disease indications — NSCLC, breast cancer, myeloma, and Alzheimer's.

Lung Cancer (NSCLC) Licensing Deal Benchmarks

NSCLC licensing deals average $1.6B total value at Phase 2. Benchmark deal terms for non-small cell lung cancer licensing agreements.

Median Upfront: $258MTotal Deal Value: $1.6B
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Breast Cancer (TNBC) Licensing Deal Benchmarks

TNBC licensing deals average $2.5B total value at Phase 2. Benchmark upfronts, milestones, and royalties for triple-negative breast cancer deals.

Median Upfront: $393MTotal Deal Value: $2.5B
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Alzheimer's Disease Licensing Deal Benchmarks

Alzheimer's licensing deals average $3.5B total value at Phase 2. Benchmark deal terms for Alzheimer's disease-modifying and symptomatic therapies.

Median Upfront: $390MTotal Deal Value: $3.5B
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Multiple Myeloma Licensing Deal Benchmarks

Multiple myeloma licensing deals average $2.4B total value at Phase 2. Benchmark upfronts, milestones, and royalties for myeloma deals.

Median Upfront: $383MTotal Deal Value: $2.4B
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NASH/MASH Deal Benchmarks 2026

NASH/MASH licensing deals average $3.1B total value. Benchmark deal terms for steatohepatitis therapies following resmetirom approval.

Median Upfront: $654MTotal Deal Value: $3.1B
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Parkinson's Disease Licensing Deal Benchmarks

Parkinson's disease licensing deals average $3.1B total value at Phase 2. Benchmark PD deal terms, milestones, and royalties.

Median Upfront: $357MTotal Deal Value: $3.1B
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Lung Cancer (NSCLC) — Deal Benchmarks & Valuation

Lung Cancer (NSCLC) licensing deals average $1.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for lung cancer (nsclc) transactions.

Median Upfront: $258MTotal Deal Value: $1.6B
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Lung Cancer (SCLC) — Deal Benchmarks & Valuation

Lung Cancer (SCLC) licensing deals average $2.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for lung cancer (sclc) transactions.

Median Upfront: $393MTotal Deal Value: $2.5B
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Breast Cancer (HER2+) — Deal Benchmarks & Valuation

Breast Cancer (HER2+) licensing deals average $2.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for breast cancer (her2+) transactions.

Median Upfront: $400MTotal Deal Value: $2.5B
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Breast Cancer (TNBC) — Deal Benchmarks & Valuation

Breast Cancer (TNBC) licensing deals average $2.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for breast cancer (tnbc) transactions.

Median Upfront: $393MTotal Deal Value: $2.5B
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Breast Cancer (HR+) — Deal Benchmarks & Valuation

Breast Cancer (HR+) licensing deals average $1.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for breast cancer (hr+) transactions.

Median Upfront: $229MTotal Deal Value: $1.5B
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Colorectal Cancer — Deal Benchmarks & Valuation

Colorectal Cancer licensing deals average $2.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for colorectal cancer transactions.

Median Upfront: $316MTotal Deal Value: $2.0B
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Pancreatic Cancer — Deal Benchmarks & Valuation

Pancreatic Cancer licensing deals average $1.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for pancreatic cancer transactions.

Median Upfront: $263MTotal Deal Value: $1.7B
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Melanoma — Deal Benchmarks & Valuation

Melanoma licensing deals average $1.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for melanoma transactions.

Median Upfront: $244MTotal Deal Value: $1.6B
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Prostate Cancer (mCRPC) — Deal Benchmarks & Valuation

Prostate Cancer (mCRPC) licensing deals average $2.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for prostate cancer (mcrpc) transactions.

Median Upfront: $425MTotal Deal Value: $2.7B
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Ovarian Cancer — Deal Benchmarks & Valuation

Ovarian Cancer licensing deals average $2.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for ovarian cancer transactions.

Median Upfront: $339MTotal Deal Value: $2.2B
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Gastric / GEJ Cancer — Deal Benchmarks & Valuation

Gastric / GEJ Cancer licensing deals average $2.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for gastric / gej cancer transactions.

Median Upfront: $309MTotal Deal Value: $2.0B
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Liver Cancer (HCC) — Deal Benchmarks & Valuation

Liver Cancer (HCC) licensing deals average $1.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for liver cancer (hcc) transactions.

Median Upfront: $253MTotal Deal Value: $1.6B
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Renal Cell Carcinoma (RCC) — Deal Benchmarks & Valuation

Renal Cell Carcinoma (RCC) licensing deals average $1.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for renal cell carcinoma (rcc) transactions.

Median Upfront: $226MTotal Deal Value: $1.4B
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Glioblastoma (GBM) — Deal Benchmarks & Valuation

Glioblastoma (GBM) licensing deals average $1.4B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for glioblastoma (gbm) transactions.

Median Upfront: $142MTotal Deal Value: $1.4B
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Bladder Cancer — Deal Benchmarks & Valuation

Bladder Cancer licensing deals average $2.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for bladder cancer transactions.

Median Upfront: $366MTotal Deal Value: $2.3B
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Head & Neck Cancer — Deal Benchmarks & Valuation

Head & Neck Cancer licensing deals average $1.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for head & neck cancer transactions.

Median Upfront: $230MTotal Deal Value: $1.5B
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Cholangiocarcinoma — Deal Benchmarks & Valuation

Cholangiocarcinoma licensing deals average $1.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for cholangiocarcinoma transactions.

Median Upfront: $251MTotal Deal Value: $1.6B
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Mesothelioma — Deal Benchmarks & Valuation

Mesothelioma licensing deals average $1.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for mesothelioma transactions.

Median Upfront: $253MTotal Deal Value: $1.6B
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Sarcoma — Deal Benchmarks & Valuation

Sarcoma licensing deals average $1.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for sarcoma transactions.

Median Upfront: $241MTotal Deal Value: $1.5B
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Endometrial Cancer — Deal Benchmarks & Valuation

Endometrial Cancer licensing deals average $1.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for endometrial cancer transactions.

Median Upfront: $248MTotal Deal Value: $1.6B
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Cervical Cancer — Deal Benchmarks & Valuation

Cervical Cancer licensing deals average $2.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for cervical cancer transactions.

Median Upfront: $339MTotal Deal Value: $2.2B
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Thyroid Cancer — Deal Benchmarks & Valuation

Thyroid Cancer licensing deals average $1.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for thyroid cancer transactions.

Median Upfront: $251MTotal Deal Value: $1.6B
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Esophageal Cancer — Deal Benchmarks & Valuation

Esophageal Cancer licensing deals average $1.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for esophageal cancer transactions.

Median Upfront: $235MTotal Deal Value: $1.5B
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Neuroendocrine Tumors (NET) — Deal Benchmarks & Valuation

Neuroendocrine Tumors (NET) licensing deals average $2.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for neuroendocrine tumors (net) transactions.

Median Upfront: $396MTotal Deal Value: $2.5B
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Uveal Melanoma — Deal Benchmarks & Valuation

Uveal Melanoma licensing deals average $1.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for uveal melanoma transactions.

Median Upfront: $266MTotal Deal Value: $1.7B
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Merkel Cell Carcinoma — Deal Benchmarks & Valuation

Merkel Cell Carcinoma licensing deals average $1.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for merkel cell carcinoma transactions.

Median Upfront: $262MTotal Deal Value: $1.7B
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Testicular Cancer — Deal Benchmarks & Valuation

Testicular Cancer licensing deals average $1.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for testicular cancer transactions.

Median Upfront: $206MTotal Deal Value: $1.3B
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Nasopharyngeal Carcinoma — Deal Benchmarks & Valuation

Nasopharyngeal Carcinoma licensing deals average $1.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for nasopharyngeal carcinoma transactions.

Median Upfront: $241MTotal Deal Value: $1.5B
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KRAS-Mutant Tumors — Deal Benchmarks & Valuation

KRAS-Mutant Tumors licensing deals average $1.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for kras-mutant tumors transactions.

Median Upfront: $220MTotal Deal Value: $1.4B
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HER2-Low Tumors — Deal Benchmarks & Valuation

HER2-Low Tumors licensing deals average $2.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for her2-low tumors transactions.

Median Upfront: $319MTotal Deal Value: $2.0B
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MSI-High / dMMR Tumors — Deal Benchmarks & Valuation

MSI-High / dMMR Tumors licensing deals average $1.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for msi-high / dmmr tumors transactions.

Median Upfront: $226MTotal Deal Value: $1.4B
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Acute Myeloid Leukemia (AML) — Deal Benchmarks & Valuation

Acute Myeloid Leukemia (AML) licensing deals average $2.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for acute myeloid leukemia (aml) transactions.

Median Upfront: $339MTotal Deal Value: $2.2B
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Acute Lymphoblastic Leukemia (ALL) — Deal Benchmarks & Valuation

Acute Lymphoblastic Leukemia (ALL) licensing deals average $1.0B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for acute lymphoblastic leukemia (all) transactions.

Median Upfront: $103MTotal Deal Value: $1.0B
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Chronic Lymphocytic Leukemia (CLL) — Deal Benchmarks & Valuation

Chronic Lymphocytic Leukemia (CLL) licensing deals average $1.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for chronic lymphocytic leukemia (cll) transactions.

Median Upfront: $220MTotal Deal Value: $1.4B
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Multiple Myeloma — Deal Benchmarks & Valuation

Multiple Myeloma licensing deals average $2.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for multiple myeloma transactions.

Median Upfront: $383MTotal Deal Value: $2.4B
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Diffuse Large B-Cell Lymphoma (DLBCL) — Deal Benchmarks & Valuation

Diffuse Large B-Cell Lymphoma (DLBCL) licensing deals average $1.0B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for diffuse large b-cell lymphoma (dlbcl) transactions.

Median Upfront: $104MTotal Deal Value: $1.0B
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Follicular Lymphoma — Deal Benchmarks & Valuation

Follicular Lymphoma licensing deals average $1.9B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for follicular lymphoma transactions.

Median Upfront: $297MTotal Deal Value: $1.9B
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Mantle Cell Lymphoma — Deal Benchmarks & Valuation

Mantle Cell Lymphoma licensing deals average $1.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for mantle cell lymphoma transactions.

Median Upfront: $237MTotal Deal Value: $1.5B
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Myelodysplastic Syndromes (MDS) — Deal Benchmarks & Valuation

Myelodysplastic Syndromes (MDS) licensing deals average $1.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for myelodysplastic syndromes (mds) transactions.

Median Upfront: $246MTotal Deal Value: $1.6B
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Hodgkin Lymphoma — Deal Benchmarks & Valuation

Hodgkin Lymphoma licensing deals average $2.1B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for hodgkin lymphoma transactions.

Median Upfront: $332MTotal Deal Value: $2.1B
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Myeloproliferative Neoplasms (MPN) — Deal Benchmarks & Valuation

Myeloproliferative Neoplasms (MPN) licensing deals average $1.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for myeloproliferative neoplasms (mpn) transactions.

Median Upfront: $237MTotal Deal Value: $1.5B
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T-Cell Lymphoma — Deal Benchmarks & Valuation

T-Cell Lymphoma licensing deals average $1.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for t-cell lymphoma transactions.

Median Upfront: $262MTotal Deal Value: $1.7B
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Alzheimer's Disease — Deal Benchmarks & Valuation

Alzheimer's Disease licensing deals average $3.1B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for alzheimer's disease transactions.

Median Upfront: $354MTotal Deal Value: $3.1B
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ALS (Amyotrophic Lateral Sclerosis) — Deal Benchmarks & Valuation

ALS (Amyotrophic Lateral Sclerosis) licensing deals average $3.9B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for als (amyotrophic lateral sclerosis) transactions.

Median Upfront: $433MTotal Deal Value: $3.9B
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Huntington's Disease — Deal Benchmarks & Valuation

Huntington's Disease licensing deals average $2.1B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for huntington's disease transactions.

Median Upfront: $140MTotal Deal Value: $2.1B
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Multiple Sclerosis — Deal Benchmarks & Valuation

Multiple Sclerosis licensing deals average $2.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for multiple sclerosis transactions.

Median Upfront: $259MTotal Deal Value: $2.3B
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Epilepsy — Deal Benchmarks & Valuation

Epilepsy licensing deals average $2.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for epilepsy transactions.

Median Upfront: $300MTotal Deal Value: $2.7B
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Migraine — Deal Benchmarks & Valuation

Migraine licensing deals average $2.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for migraine transactions.

Median Upfront: $292MTotal Deal Value: $2.6B
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Schizophrenia — Deal Benchmarks & Valuation

Schizophrenia licensing deals average $2.9B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for schizophrenia transactions.

Median Upfront: $324MTotal Deal Value: $2.9B
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Depression / MDD — Deal Benchmarks & Valuation

Depression / MDD licensing deals average $2.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for depression / mdd transactions.

Median Upfront: $291MTotal Deal Value: $2.6B
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Chronic / Neuropathic Pain — Deal Benchmarks & Valuation

Chronic / Neuropathic Pain licensing deals average $2.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for chronic / neuropathic pain transactions.

Median Upfront: $271MTotal Deal Value: $2.4B
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Narcolepsy — Deal Benchmarks & Valuation

Narcolepsy licensing deals average $2.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for narcolepsy transactions.

Median Upfront: $307MTotal Deal Value: $2.7B
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Autism Spectrum Disorder — Deal Benchmarks & Valuation

Autism Spectrum Disorder licensing deals average $2.9B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for autism spectrum disorder transactions.

Median Upfront: $324MTotal Deal Value: $2.9B
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Rett Syndrome — Deal Benchmarks & Valuation

Rett Syndrome licensing deals average $1.7B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for rett syndrome transactions.

Median Upfront: $118MTotal Deal Value: $1.7B
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Spinal Muscular Atrophy (SMA) — Deal Benchmarks & Valuation

Spinal Muscular Atrophy (SMA) licensing deals average $1.8B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for spinal muscular atrophy (sma) transactions.

Median Upfront: $122MTotal Deal Value: $1.8B
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Angelman Syndrome — Deal Benchmarks & Valuation

Angelman Syndrome licensing deals average $1.8B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for angelman syndrome transactions.

Median Upfront: $125MTotal Deal Value: $1.8B
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Dravet Syndrome — Deal Benchmarks & Valuation

Dravet Syndrome licensing deals average $3.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for dravet syndrome transactions.

Median Upfront: $367MTotal Deal Value: $3.3B
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Addiction / Substance Use Disorders — Deal Benchmarks & Valuation

Addiction / Substance Use Disorders licensing deals average $2.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for addiction / substance use disorders transactions.

Median Upfront: $283MTotal Deal Value: $2.5B
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Bipolar Disorder — Deal Benchmarks & Valuation

Bipolar Disorder licensing deals average $2.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for bipolar disorder transactions.

Median Upfront: $295MTotal Deal Value: $2.6B
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PTSD — Deal Benchmarks & Valuation

PTSD licensing deals average $3.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for ptsd transactions.

Median Upfront: $357MTotal Deal Value: $3.2B
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OCD / Anxiety Disorders — Deal Benchmarks & Valuation

OCD / Anxiety Disorders licensing deals average $2.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for ocd / anxiety disorders transactions.

Median Upfront: $283MTotal Deal Value: $2.5B
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Traumatic Brain Injury — Deal Benchmarks & Valuation

Traumatic Brain Injury licensing deals average $2.8B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for traumatic brain injury transactions.

Median Upfront: $315MTotal Deal Value: $2.8B
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Duchenne Muscular Dystrophy (Neuro) — Deal Benchmarks & Valuation

Duchenne Muscular Dystrophy (Neuro) licensing deals average $1.8B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for duchenne muscular dystrophy (neuro) transactions.

Median Upfront: $122MTotal Deal Value: $1.8B
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Friedreich's Ataxia — Deal Benchmarks & Valuation

Friedreich's Ataxia licensing deals average $1.7B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for friedreich's ataxia transactions.

Median Upfront: $117MTotal Deal Value: $1.7B
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Frontotemporal Dementia (FTD) — Deal Benchmarks & Valuation

Frontotemporal Dementia (FTD) licensing deals average $1.6B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for frontotemporal dementia (ftd) transactions.

Median Upfront: $111MTotal Deal Value: $1.6B
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Lewy Body Dementia — Deal Benchmarks & Valuation

Lewy Body Dementia licensing deals average $3.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for lewy body dementia transactions.

Median Upfront: $334MTotal Deal Value: $3.0B
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Myotonic Dystrophy — Deal Benchmarks & Valuation

Myotonic Dystrophy licensing deals average $2.0B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for myotonic dystrophy transactions.

Median Upfront: $134MTotal Deal Value: $2.0B
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Movement Disorders / Tremor — Deal Benchmarks & Valuation

Movement Disorders / Tremor licensing deals average $2.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for movement disorders / tremor transactions.

Median Upfront: $295MTotal Deal Value: $2.6B
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ADHD — Deal Benchmarks & Valuation

ADHD licensing deals average $2.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for adhd transactions.

Median Upfront: $271MTotal Deal Value: $2.4B
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Insomnia — Deal Benchmarks & Valuation

Insomnia licensing deals average $2.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for insomnia transactions.

Median Upfront: $252MTotal Deal Value: $2.2B
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Rheumatoid Arthritis — Deal Benchmarks & Valuation

Rheumatoid Arthritis licensing deals average $2.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for rheumatoid arthritis transactions.

Median Upfront: $480MTotal Deal Value: $2.5B
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Systemic Lupus (SLE) — Deal Benchmarks & Valuation

Systemic Lupus (SLE) licensing deals average $3.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for systemic lupus (sle) transactions.

Median Upfront: $581MTotal Deal Value: $3.0B
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Lupus Nephritis — Deal Benchmarks & Valuation

Lupus Nephritis licensing deals average $3.1B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for lupus nephritis transactions.

Median Upfront: $592MTotal Deal Value: $3.1B
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Atopic Dermatitis (Immunology) — Deal Benchmarks & Valuation

Atopic Dermatitis (Immunology) licensing deals average $2.8B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for atopic dermatitis (immunology) transactions.

Median Upfront: $541MTotal Deal Value: $2.8B
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Psoriasis (Immunology) — Deal Benchmarks & Valuation

Psoriasis (Immunology) licensing deals average $2.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for psoriasis (immunology) transactions.

Median Upfront: $521MTotal Deal Value: $2.7B
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Ulcerative Colitis — Deal Benchmarks & Valuation

Ulcerative Colitis licensing deals average $4.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for ulcerative colitis transactions.

Median Upfront: $853MTotal Deal Value: $4.4B
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Crohn's Disease (Immunology) — Deal Benchmarks & Valuation

Crohn's Disease (Immunology) licensing deals average $4.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for crohn's disease (immunology) transactions.

Median Upfront: $881MTotal Deal Value: $4.6B
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Myasthenia Gravis — Deal Benchmarks & Valuation

Myasthenia Gravis licensing deals average $4.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for myasthenia gravis transactions.

Median Upfront: $801MTotal Deal Value: $4.2B
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IgA Nephropathy — Deal Benchmarks & Valuation

IgA Nephropathy licensing deals average $3.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for iga nephropathy transactions.

Median Upfront: $608MTotal Deal Value: $3.2B
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ANCA Vasculitis — Deal Benchmarks & Valuation

ANCA Vasculitis licensing deals average $3.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for anca vasculitis transactions.

Median Upfront: $676MTotal Deal Value: $3.5B
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Hidradenitis Suppurativa — Deal Benchmarks & Valuation

Hidradenitis Suppurativa licensing deals average $2.8B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for hidradenitis suppurativa transactions.

Median Upfront: $541MTotal Deal Value: $2.8B
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Severe Asthma — Deal Benchmarks & Valuation

Severe Asthma licensing deals average $2.9B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for severe asthma transactions.

Median Upfront: $561MTotal Deal Value: $2.9B
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Eosinophilic Esophagitis (EoE) — Deal Benchmarks & Valuation

Eosinophilic Esophagitis (EoE) licensing deals average $3.1B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for eosinophilic esophagitis (eoe) transactions.

Median Upfront: $597MTotal Deal Value: $3.1B
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Graft-vs-Host Disease (GVHD) — Deal Benchmarks & Valuation

Graft-vs-Host Disease (GVHD) licensing deals average $3.5B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for graft-vs-host disease (gvhd) transactions.

Median Upfront: $355MTotal Deal Value: $3.5B
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CIDP — Deal Benchmarks & Valuation

CIDP licensing deals average $3.8B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for cidp transactions.

Median Upfront: $735MTotal Deal Value: $3.8B
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PNH — Deal Benchmarks & Valuation

PNH licensing deals average $4.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for pnh transactions.

Median Upfront: $773MTotal Deal Value: $4.0B
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Systemic Sclerosis — Deal Benchmarks & Valuation

Systemic Sclerosis licensing deals average $3.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for systemic sclerosis transactions.

Median Upfront: $569MTotal Deal Value: $3.0B
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Sjogren's Syndrome — Deal Benchmarks & Valuation

Sjogren's Syndrome licensing deals average $2.9B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for sjogren's syndrome transactions.

Median Upfront: $553MTotal Deal Value: $2.9B
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Idiopathic Pulmonary Fibrosis (IPF) — Deal Benchmarks & Valuation

Idiopathic Pulmonary Fibrosis (IPF) licensing deals average $3.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for idiopathic pulmonary fibrosis (ipf) transactions.

Median Upfront: $569MTotal Deal Value: $3.0B
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COPD (Immunology) — Deal Benchmarks & Valuation

COPD (Immunology) licensing deals average $2.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for copd (immunology) transactions.

Median Upfront: $513MTotal Deal Value: $2.7B
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Ankylosing Spondylitis — Deal Benchmarks & Valuation

Ankylosing Spondylitis licensing deals average $2.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for ankylosing spondylitis transactions.

Median Upfront: $521MTotal Deal Value: $2.7B
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Giant Cell Arteritis — Deal Benchmarks & Valuation

Giant Cell Arteritis licensing deals average $3.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for giant cell arteritis transactions.

Median Upfront: $569MTotal Deal Value: $3.0B
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Pemphigus — Deal Benchmarks & Valuation

Pemphigus licensing deals average $3.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for pemphigus transactions.

Median Upfront: $581MTotal Deal Value: $3.0B
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Immune Thrombocytopenia (ITP) — Deal Benchmarks & Valuation

Immune Thrombocytopenia (ITP) licensing deals average $2.8B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for immune thrombocytopenia (itp) transactions.

Median Upfront: $541MTotal Deal Value: $2.8B
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Vitiligo (Immunology) — Deal Benchmarks & Valuation

Vitiligo (Immunology) licensing deals average $2.9B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for vitiligo (immunology) transactions.

Median Upfront: $548MTotal Deal Value: $2.9B
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Multiple Sclerosis (Immunology) — Deal Benchmarks & Valuation

Multiple Sclerosis (Immunology) licensing deals average $2.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for multiple sclerosis (immunology) transactions.

Median Upfront: $521MTotal Deal Value: $2.7B
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Obesity — Deal Benchmarks & Valuation

Obesity licensing deals average $4.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for obesity transactions.

Median Upfront: $935MTotal Deal Value: $4.5B
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Type 2 Diabetes — Deal Benchmarks & Valuation

Type 2 Diabetes licensing deals average $4.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for type 2 diabetes transactions.

Median Upfront: $816MTotal Deal Value: $4.0B
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NASH / MASH — Deal Benchmarks & Valuation

NASH / MASH licensing deals average $3.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for nash / mash transactions.

Median Upfront: $701MTotal Deal Value: $3.3B
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Type 1 Diabetes — Deal Benchmarks & Valuation

Type 1 Diabetes licensing deals average $3.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for type 1 diabetes transactions.

Median Upfront: $672MTotal Deal Value: $3.2B
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Gout — Deal Benchmarks & Valuation

Gout licensing deals average $2.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for gout transactions.

Median Upfront: $552MTotal Deal Value: $2.6B
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Fabry Disease — Deal Benchmarks & Valuation

Fabry Disease licensing deals average $2.2B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for fabry disease transactions.

Median Upfront: $274MTotal Deal Value: $2.2B
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Gaucher Disease — Deal Benchmarks & Valuation

Gaucher Disease licensing deals average $3.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for gaucher disease transactions.

Median Upfront: $640MTotal Deal Value: $3.0B
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Pompe Disease — Deal Benchmarks & Valuation

Pompe Disease licensing deals average $2.0B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for pompe disease transactions.

Median Upfront: $249MTotal Deal Value: $2.0B
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Phenylketonuria (PKU) — Deal Benchmarks & Valuation

Phenylketonuria (PKU) licensing deals average $1.9B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for phenylketonuria (pku) transactions.

Median Upfront: $239MTotal Deal Value: $1.9B
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Metabolic Syndrome — Deal Benchmarks & Valuation

Metabolic Syndrome licensing deals average $4.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for metabolic syndrome transactions.

Median Upfront: $962MTotal Deal Value: $4.7B
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CKD (Metabolic) — Deal Benchmarks & Valuation

CKD (Metabolic) licensing deals average $3.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for ckd (metabolic) transactions.

Median Upfront: $627MTotal Deal Value: $3.0B
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Familial Hypercholesterolemia — Deal Benchmarks & Valuation

Familial Hypercholesterolemia licensing deals average $2.9B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for familial hypercholesterolemia transactions.

Median Upfront: $609MTotal Deal Value: $2.9B
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ATTR Amyloidosis — Deal Benchmarks & Valuation

ATTR Amyloidosis licensing deals average $3.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for attr amyloidosis transactions.

Median Upfront: $670MTotal Deal Value: $3.2B
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Heart Failure (HFrEF) — Deal Benchmarks & Valuation

Heart Failure (HFrEF) licensing deals average $3.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for heart failure (hfref) transactions.

Median Upfront: $606MTotal Deal Value: $3.0B
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Atrial Fibrillation — Deal Benchmarks & Valuation

Atrial Fibrillation licensing deals average $2.9B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for atrial fibrillation transactions.

Median Upfront: $583MTotal Deal Value: $2.9B
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Pulmonary Arterial Hypertension — Deal Benchmarks & Valuation

Pulmonary Arterial Hypertension licensing deals average $3.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for pulmonary arterial hypertension transactions.

Median Upfront: $664MTotal Deal Value: $3.3B
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Dyslipidemia — Deal Benchmarks & Valuation

Dyslipidemia licensing deals average $3.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for dyslipidemia transactions.

Median Upfront: $736MTotal Deal Value: $3.7B
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Cardiomyopathy — Deal Benchmarks & Valuation

Cardiomyopathy licensing deals average $4.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for cardiomyopathy transactions.

Median Upfront: $928MTotal Deal Value: $4.7B
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Hypertrophic Cardiomyopathy (HCM) — Deal Benchmarks & Valuation

Hypertrophic Cardiomyopathy (HCM) licensing deals average $4.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for hypertrophic cardiomyopathy (hcm) transactions.

Median Upfront: $845MTotal Deal Value: $4.3B
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Coronary Artery Disease — Deal Benchmarks & Valuation

Coronary Artery Disease licensing deals average $2.8B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for coronary artery disease transactions.

Median Upfront: $561MTotal Deal Value: $2.8B
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Peripheral Artery Disease — Deal Benchmarks & Valuation

Peripheral Artery Disease licensing deals average $3.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for peripheral artery disease transactions.

Median Upfront: $592MTotal Deal Value: $3.0B
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Resistant Hypertension — Deal Benchmarks & Valuation

Resistant Hypertension licensing deals average $3.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for resistant hypertension transactions.

Median Upfront: $606MTotal Deal Value: $3.0B
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Stroke Prevention — Deal Benchmarks & Valuation

Stroke Prevention licensing deals average $3.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for stroke prevention transactions.

Median Upfront: $689MTotal Deal Value: $3.5B
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Heart Failure (HFpEF) — Deal Benchmarks & Valuation

Heart Failure (HFpEF) licensing deals average $3.1B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for heart failure (hfpef) transactions.

Median Upfront: $619MTotal Deal Value: $3.1B
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HIV / AIDS — Deal Benchmarks & Valuation

HIV / AIDS licensing deals average $2.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for hiv / aids transactions.

Median Upfront: $604MTotal Deal Value: $2.3B
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Hepatitis B (HBV) — Deal Benchmarks & Valuation

Hepatitis B (HBV) licensing deals average $2.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for hepatitis b (hbv) transactions.

Median Upfront: $648MTotal Deal Value: $2.5B
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RSV — Deal Benchmarks & Valuation

RSV licensing deals average $3.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for rsv transactions.

Median Upfront: $826MTotal Deal Value: $3.2B
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Influenza — Deal Benchmarks & Valuation

Influenza licensing deals average $3.1B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for influenza transactions.

Median Upfront: $804MTotal Deal Value: $3.1B
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Tuberculosis — Deal Benchmarks & Valuation

Tuberculosis licensing deals average $2.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for tuberculosis transactions.

Median Upfront: $710MTotal Deal Value: $2.7B
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AMR Bacterial Infections — Deal Benchmarks & Valuation

AMR Bacterial Infections licensing deals average $3.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for amr bacterial infections transactions.

Median Upfront: $837MTotal Deal Value: $3.2B
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Invasive Fungal Infections — Deal Benchmarks & Valuation

Invasive Fungal Infections licensing deals average $2.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for invasive fungal infections transactions.

Median Upfront: $635MTotal Deal Value: $2.4B
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COVID-19 — Deal Benchmarks & Valuation

COVID-19 licensing deals average $2.1B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for covid-19 transactions.

Median Upfront: $539MTotal Deal Value: $2.1B
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Hepatitis D (HDV) — Deal Benchmarks & Valuation

Hepatitis D (HDV) licensing deals average $2.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for hepatitis d (hdv) transactions.

Median Upfront: $670MTotal Deal Value: $2.6B
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CMV Infection — Deal Benchmarks & Valuation

CMV Infection licensing deals average $2.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for cmv infection transactions.

Median Upfront: $664MTotal Deal Value: $2.5B
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C. difficile Infection — Deal Benchmarks & Valuation

C. difficile Infection licensing deals average $2.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for c. difficile infection transactions.

Median Upfront: $636MTotal Deal Value: $2.4B
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Wet AMD — Deal Benchmarks & Valuation

Wet AMD licensing deals average $3.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for wet amd transactions.

Median Upfront: $768MTotal Deal Value: $3.6B
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Dry AMD / Geographic Atrophy — Deal Benchmarks & Valuation

Dry AMD / Geographic Atrophy licensing deals average $3.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for dry amd / geographic atrophy transactions.

Median Upfront: $682MTotal Deal Value: $3.2B
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Diabetic Retinopathy — Deal Benchmarks & Valuation

Diabetic Retinopathy licensing deals average $3.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for diabetic retinopathy transactions.

Median Upfront: $682MTotal Deal Value: $3.2B
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Glaucoma — Deal Benchmarks & Valuation

Glaucoma licensing deals average $2.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for glaucoma transactions.

Median Upfront: $570MTotal Deal Value: $2.7B
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Dry Eye Disease — Deal Benchmarks & Valuation

Dry Eye Disease licensing deals average $2.1B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for dry eye disease transactions.

Median Upfront: $454MTotal Deal Value: $2.1B
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Retinitis Pigmentosa — Deal Benchmarks & Valuation

Retinitis Pigmentosa licensing deals average $2.3B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for retinitis pigmentosa transactions.

Median Upfront: $331MTotal Deal Value: $2.3B
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Diabetic Macular Edema — Deal Benchmarks & Valuation

Diabetic Macular Edema licensing deals average $3.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for diabetic macular edema transactions.

Median Upfront: $737MTotal Deal Value: $3.5B
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Myopia Progression — Deal Benchmarks & Valuation

Myopia Progression licensing deals average $2.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for myopia progression transactions.

Median Upfront: $461MTotal Deal Value: $2.2B
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Stargardt Disease — Deal Benchmarks & Valuation

Stargardt Disease licensing deals average $1.9B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for stargardt disease transactions.

Median Upfront: $280MTotal Deal Value: $1.9B
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Spinal Muscular Atrophy (SMA) — Deal Benchmarks & Valuation

Spinal Muscular Atrophy (SMA) licensing deals average $2.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for spinal muscular atrophy (sma) transactions.

Median Upfront: $363MTotal Deal Value: $2.0B
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Duchenne Muscular Dystrophy — Deal Benchmarks & Valuation

Duchenne Muscular Dystrophy licensing deals average $1.0B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for duchenne muscular dystrophy transactions.

Median Upfront: $112MTotal Deal Value: $1.0B
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Cystic Fibrosis — Deal Benchmarks & Valuation

Cystic Fibrosis licensing deals average $2.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for cystic fibrosis transactions.

Median Upfront: $420MTotal Deal Value: $2.3B
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Fabry Disease — Deal Benchmarks & Valuation

Fabry Disease licensing deals average $2.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for fabry disease transactions.

Median Upfront: $432MTotal Deal Value: $2.3B
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Gaucher Disease — Deal Benchmarks & Valuation

Gaucher Disease licensing deals average $2.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for gaucher disease transactions.

Median Upfront: $424MTotal Deal Value: $2.3B
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Pompe Disease — Deal Benchmarks & Valuation

Pompe Disease licensing deals average $2.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for pompe disease transactions.

Median Upfront: $421MTotal Deal Value: $2.3B
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Hemophilia A — Deal Benchmarks & Valuation

Hemophilia A licensing deals average $1.9B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for hemophilia a transactions.

Median Upfront: $335MTotal Deal Value: $1.9B
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Hemophilia B — Deal Benchmarks & Valuation

Hemophilia B licensing deals average $1.8B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for hemophilia b transactions.

Median Upfront: $326MTotal Deal Value: $1.8B
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Sickle Cell Disease — Deal Benchmarks & Valuation

Sickle Cell Disease licensing deals average $1.1B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for sickle cell disease transactions.

Median Upfront: $119MTotal Deal Value: $1.1B
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Huntington's Disease (Rare) — Deal Benchmarks & Valuation

Huntington's Disease (Rare) licensing deals average $1.3B total value at Phase 1. Benchmark upfront payments, milestones, and royalties for huntington's disease (rare) transactions.

Median Upfront: $140MTotal Deal Value: $1.3B
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Beta-Thalassemia — Deal Benchmarks & Valuation

Beta-Thalassemia licensing deals average $1.9B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for beta-thalassemia transactions.

Median Upfront: $352MTotal Deal Value: $1.9B
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Mucopolysaccharidosis (MPS) — Deal Benchmarks & Valuation

Mucopolysaccharidosis (MPS) licensing deals average $2.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for mucopolysaccharidosis (mps) transactions.

Median Upfront: $449MTotal Deal Value: $2.4B
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Niemann-Pick Type C — Deal Benchmarks & Valuation

Niemann-Pick Type C licensing deals average $2.2B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for niemann-pick type c transactions.

Median Upfront: $411MTotal Deal Value: $2.2B
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Fragile X Syndrome — Deal Benchmarks & Valuation

Fragile X Syndrome licensing deals average $2.1B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for fragile x syndrome transactions.

Median Upfront: $393MTotal Deal Value: $2.1B
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Follicular Lymphoma — Deal Benchmarks & Valuation

Follicular Lymphoma licensing deals average $3.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for follicular lymphoma transactions.

Median Upfront: $678MTotal Deal Value: $3.4B
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Myelofibrosis — Deal Benchmarks & Valuation

Myelofibrosis licensing deals average $3.1B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for myelofibrosis transactions.

Median Upfront: $636MTotal Deal Value: $3.1B
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Aplastic Anemia — Deal Benchmarks & Valuation

Aplastic Anemia licensing deals average $3.1B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for aplastic anemia transactions.

Median Upfront: $622MTotal Deal Value: $3.1B
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Polycythemia Vera — Deal Benchmarks & Valuation

Polycythemia Vera licensing deals average $2.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for polycythemia vera transactions.

Median Upfront: $555MTotal Deal Value: $2.7B
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Waldenstrom's Macroglobulinemia — Deal Benchmarks & Valuation

Waldenstrom's Macroglobulinemia licensing deals average $2.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for waldenstrom's macroglobulinemia transactions.

Median Upfront: $543MTotal Deal Value: $2.7B
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Mantle Cell Lymphoma (Heme) — Deal Benchmarks & Valuation

Mantle Cell Lymphoma (Heme) licensing deals average $2.9B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for mantle cell lymphoma (heme) transactions.

Median Upfront: $596MTotal Deal Value: $2.9B
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Hodgkin Lymphoma (Heme) — Deal Benchmarks & Valuation

Hodgkin Lymphoma (Heme) licensing deals average $2.8B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for hodgkin lymphoma (heme) transactions.

Median Upfront: $572MTotal Deal Value: $2.8B
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Atopic Dermatitis — Deal Benchmarks & Valuation

Atopic Dermatitis licensing deals average $2.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for atopic dermatitis transactions.

Median Upfront: $441MTotal Deal Value: $2.4B
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Alopecia Areata — Deal Benchmarks & Valuation

Alopecia Areata licensing deals average $1.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for alopecia areata transactions.

Median Upfront: $303MTotal Deal Value: $1.7B
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Hidradenitis Suppurativa — Deal Benchmarks & Valuation

Hidradenitis Suppurativa licensing deals average $2.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for hidradenitis suppurativa transactions.

Median Upfront: $418MTotal Deal Value: $2.3B
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Chronic Urticaria — Deal Benchmarks & Valuation

Chronic Urticaria licensing deals average $2.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for chronic urticaria transactions.

Median Upfront: $375MTotal Deal Value: $2.0B
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Acne — Deal Benchmarks & Valuation

Acne licensing deals average $1.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for acne transactions.

Median Upfront: $306MTotal Deal Value: $1.6B
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Rosacea — Deal Benchmarks & Valuation

Rosacea licensing deals average $1.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for rosacea transactions.

Median Upfront: $319MTotal Deal Value: $1.7B
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Prurigo Nodularis — Deal Benchmarks & Valuation

Prurigo Nodularis licensing deals average $2.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for prurigo nodularis transactions.

Median Upfront: $380MTotal Deal Value: $2.0B
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Crohn's Disease — Deal Benchmarks & Valuation

Crohn's Disease licensing deals average $3.3B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for crohn's disease transactions.

Median Upfront: $632MTotal Deal Value: $3.3B
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Celiac Disease — Deal Benchmarks & Valuation

Celiac Disease licensing deals average $2.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for celiac disease transactions.

Median Upfront: $536MTotal Deal Value: $2.7B
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IBS-D — Deal Benchmarks & Valuation

IBS-D licensing deals average $1.9B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for ibs-d transactions.

Median Upfront: $381MTotal Deal Value: $1.9B
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Short Bowel Syndrome — Deal Benchmarks & Valuation

Short Bowel Syndrome licensing deals average $2.6B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for short bowel syndrome transactions.

Median Upfront: $519MTotal Deal Value: $2.6B
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Primary Biliary Cholangitis (PBC) — Deal Benchmarks & Valuation

Primary Biliary Cholangitis (PBC) licensing deals average $2.5B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for primary biliary cholangitis (pbc) transactions.

Median Upfront: $488MTotal Deal Value: $2.5B
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Microscopic Colitis — Deal Benchmarks & Valuation

Microscopic Colitis licensing deals average $2.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for microscopic colitis transactions.

Median Upfront: $462MTotal Deal Value: $2.4B
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Gastroparesis — Deal Benchmarks & Valuation

Gastroparesis licensing deals average $2.4B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for gastroparesis transactions.

Median Upfront: $462MTotal Deal Value: $2.4B
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NASH (GI) — Deal Benchmarks & Valuation

NASH (GI) licensing deals average $2.8B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for nash (gi) transactions.

Median Upfront: $552MTotal Deal Value: $2.8B
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Endometriosis — Deal Benchmarks & Valuation

Endometriosis licensing deals average $1.8B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for endometriosis transactions.

Median Upfront: $326MTotal Deal Value: $1.8B
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Uterine Fibroids — Deal Benchmarks & Valuation

Uterine Fibroids licensing deals average $1.7B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for uterine fibroids transactions.

Median Upfront: $317MTotal Deal Value: $1.7B
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PCOS — Deal Benchmarks & Valuation

PCOS licensing deals average $1.8B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for pcos transactions.

Median Upfront: $321MTotal Deal Value: $1.8B
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Menopause — Deal Benchmarks & Valuation

Menopause licensing deals average $1.8B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for menopause transactions.

Median Upfront: $335MTotal Deal Value: $1.8B
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Postpartum Depression — Deal Benchmarks & Valuation

Postpartum Depression licensing deals average $1.8B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for postpartum depression transactions.

Median Upfront: $333MTotal Deal Value: $1.8B
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Preeclampsia — Deal Benchmarks & Valuation

Preeclampsia licensing deals average $2.0B total value at Phase 2. Benchmark upfront payments, milestones, and royalties for preeclampsia transactions.

Median Upfront: $373MTotal Deal Value: $2.0B
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By Clinical Stage

Deal benchmarks across development stages — preclinical, Phase 2, and Phase 3 licensing terms.

Preclinical Licensing Deal Benchmarks

Preclinical licensing deals average $504M total value. Benchmark upfronts, milestones, and royalties for IND-enabling stage assets.

Median Upfront: $32MTotal Deal Value: $504M
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Phase 2 Licensing Deal Benchmarks

Phase 2 licensing deals average $1.6B total value. Comprehensive benchmarks for upfronts, milestones, and royalties at the proof-of-concept stage.

Median Upfront: $258MTotal Deal Value: $1.6B
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Phase 3 Licensing Deal Benchmarks

Phase 3 licensing deals average $3.1B total value with $721M upfront. Benchmark deal terms for pivotal-stage assets.

Median Upfront: $721MTotal Deal Value: $3.1B
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Preclinical Oncology Deal Benchmarks

Preclinical oncology licensing deal benchmarks: median upfront $32M, total deal value $504M, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $32MTotal Deal Value: $504M
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Phase 1 Oncology Deal Benchmarks

Phase 1 oncology licensing deal benchmarks: median upfront $90M, total deal value $882M, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $90MTotal Deal Value: $882M
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Phase 1/2 Oncology Deal Benchmarks

Phase 1/2 oncology licensing deal benchmarks: median upfront $163M, total deal value $1.3B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $163MTotal Deal Value: $1.3B
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Phase 2 Oncology Deal Benchmarks

Phase 2 oncology licensing deal benchmarks: median upfront $258M, total deal value $1.6B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $258MTotal Deal Value: $1.6B
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Phase 2/3 Oncology Deal Benchmarks

Phase 2/3 oncology licensing deal benchmarks: median upfront $470M, total deal value $2.4B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $470MTotal Deal Value: $2.4B
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Phase 3 Oncology Deal Benchmarks

Phase 3 oncology licensing deal benchmarks: median upfront $721M, total deal value $3.1B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $721MTotal Deal Value: $3.1B
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Approved Oncology Deal Benchmarks

Approved oncology licensing deal benchmarks: median upfront $2.1B, total deal value $5.7B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $2.1BTotal Deal Value: $5.7B
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Preclinical Neurology Deal Benchmarks

Preclinical neurology licensing deal benchmarks: median upfront $47M, total deal value $1.1B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $47MTotal Deal Value: $1.1B
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Phase 1 Neurology Deal Benchmarks

Phase 1 neurology licensing deal benchmarks: median upfront $112M, total deal value $1.6B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $112MTotal Deal Value: $1.6B
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Phase 1/2 Neurology Deal Benchmarks

Phase 1/2 neurology licensing deal benchmarks: median upfront $223M, total deal value $2.3B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $223MTotal Deal Value: $2.3B
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Phase 2 Neurology Deal Benchmarks

Phase 2 neurology licensing deal benchmarks: median upfront $343M, total deal value $3.0B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $343MTotal Deal Value: $3.0B
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Phase 2/3 Neurology Deal Benchmarks

Phase 2/3 neurology licensing deal benchmarks: median upfront $536M, total deal value $3.5B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $536MTotal Deal Value: $3.5B
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Phase 3 Neurology Deal Benchmarks

Phase 3 neurology licensing deal benchmarks: median upfront $770M, total deal value $4.1B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $770MTotal Deal Value: $4.1B
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Approved Neurology Deal Benchmarks

Approved neurology licensing deal benchmarks: median upfront $2.2B, total deal value $7.1B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $2.2BTotal Deal Value: $7.1B
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Preclinical Immunology & Autoimmune Deal Benchmarks

Preclinical immunology & autoimmune licensing deal benchmarks: median upfront $61M, total deal value $878M, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $61MTotal Deal Value: $878M
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Phase 1 Immunology & Autoimmune Deal Benchmarks

Phase 1 immunology & autoimmune licensing deal benchmarks: median upfront $139M, total deal value $1.3B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $139MTotal Deal Value: $1.3B
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Phase 1/2 Immunology & Autoimmune Deal Benchmarks

Phase 1/2 immunology & autoimmune licensing deal benchmarks: median upfront $284M, total deal value $1.9B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $284MTotal Deal Value: $1.9B
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Phase 2 Immunology & Autoimmune Deal Benchmarks

Phase 2 immunology & autoimmune licensing deal benchmarks: median upfront $466M, total deal value $2.4B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $466MTotal Deal Value: $2.4B
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Phase 2/3 Immunology & Autoimmune Deal Benchmarks

Phase 2/3 immunology & autoimmune licensing deal benchmarks: median upfront $562M, total deal value $2.5B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $562MTotal Deal Value: $2.5B
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Phase 3 Immunology & Autoimmune Deal Benchmarks

Phase 3 immunology & autoimmune licensing deal benchmarks: median upfront $766M, total deal value $3.0B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $766MTotal Deal Value: $3.0B
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Approved Immunology & Autoimmune Deal Benchmarks

Approved immunology & autoimmune licensing deal benchmarks: median upfront $2.9B, total deal value $7.4B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $2.9BTotal Deal Value: $7.4B
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Preclinical Metabolic & Obesity Deal Benchmarks

Preclinical metabolic & obesity licensing deal benchmarks: median upfront $90M, total deal value $1.1B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $90MTotal Deal Value: $1.1B
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Phase 1 Metabolic & Obesity Deal Benchmarks

Phase 1 metabolic & obesity licensing deal benchmarks: median upfront $265M, total deal value $2.1B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $265MTotal Deal Value: $2.1B
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Phase 1/2 Metabolic & Obesity Deal Benchmarks

Phase 1/2 metabolic & obesity licensing deal benchmarks: median upfront $437M, total deal value $2.6B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $437MTotal Deal Value: $2.6B
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Phase 2 Metabolic & Obesity Deal Benchmarks

Phase 2 metabolic & obesity licensing deal benchmarks: median upfront $683M, total deal value $3.2B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $683MTotal Deal Value: $3.2B
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Phase 2/3 Metabolic & Obesity Deal Benchmarks

Phase 2/3 metabolic & obesity licensing deal benchmarks: median upfront $1.0B, total deal value $4.2B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $1.0BTotal Deal Value: $4.2B
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Phase 3 Metabolic & Obesity Deal Benchmarks

Phase 3 metabolic & obesity licensing deal benchmarks: median upfront $1.4B, total deal value $5.3B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $1.4BTotal Deal Value: $5.3B
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Approved Metabolic & Obesity Deal Benchmarks

Approved metabolic & obesity licensing deal benchmarks: median upfront $4.0B, total deal value $10.5B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $4.0BTotal Deal Value: $10.5B
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Preclinical Rare Disease Deal Benchmarks

Preclinical rare disease licensing deal benchmarks: median upfront $36M, total deal value $499M, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $36MTotal Deal Value: $499M
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Phase 1 Rare Disease Deal Benchmarks

Phase 1 rare disease licensing deal benchmarks: median upfront $91M, total deal value $846M, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $91MTotal Deal Value: $846M
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Phase 1/2 Rare Disease Deal Benchmarks

Phase 1/2 rare disease licensing deal benchmarks: median upfront $161M, total deal value $1.1B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $161MTotal Deal Value: $1.1B
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Phase 2 Rare Disease Deal Benchmarks

Phase 2 rare disease licensing deal benchmarks: median upfront $285M, total deal value $1.6B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $285MTotal Deal Value: $1.6B
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Phase 2/3 Rare Disease Deal Benchmarks

Phase 2/3 rare disease licensing deal benchmarks: median upfront $543M, total deal value $2.4B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $543MTotal Deal Value: $2.4B
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Phase 3 Rare Disease Deal Benchmarks

Phase 3 rare disease licensing deal benchmarks: median upfront $971M, total deal value $3.4B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $971MTotal Deal Value: $3.4B
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Approved Rare Disease Deal Benchmarks

Approved rare disease licensing deal benchmarks: median upfront $2.6B, total deal value $6.3B, and royalty rates. Data from 2,500+ verified transactions.

Median Upfront: $2.6BTotal Deal Value: $6.3B
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